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SKINDIA QUIZ
Year : 2011  |  Volume : 2  |  Issue : 2  |  Page : 129-130  

SkIndia Quiz 3 - Scalp swelling in a middle-aged woman


Department of Pathology, P E S Institute of Medical Sciences and Research, Kuppam, India

Date of Web Publication14-Oct-2011

Correspondence Address:
A S Ramaswamy
52, Vignesh Nilayam, 11th Cross, T C Palya, K R Puram, Bangalore - 560 036
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.80518

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How to cite this article:
Siva Ranjan D, Ramaswamy A S, Manjunatha H K, Sunil Kumar B, Arun Kumar S P. SkIndia Quiz 3 - Scalp swelling in a middle-aged woman. Indian Dermatol Online J 2011;2:129-30

How to cite this URL:
Siva Ranjan D, Ramaswamy A S, Manjunatha H K, Sunil Kumar B, Arun Kumar S P. SkIndia Quiz 3 - Scalp swelling in a middle-aged woman. Indian Dermatol Online J [serial online] 2011 [cited 2019 Jul 20];2:129-30. Available from: http://www.idoj.in/text.asp?2011/2/2/129/80518

A 45-year old female presented with a slow growing swelling over the scalp of five years duration, with a recent history of rapid growth over the last six months [Figure 1]. An excision biopsy was done and sent for histopathological examination. Sections from the same revealed an unremarkable epidermis which showed no evidence of any actinic keratosis or any intra epithelial carcinoma. Beneath this was located a well circumscribed, but focally infiltrative neoplasm comprising lobular proliferation of squamous epithelial cells [Figure 2]. Abrupt keratinization without intervening granular layer was noted in these islands. Moderate-to-severe nuclear atypia was noted in these cells with increased mitotic activity [Figure 3]. No cytologically atypical clear cells were seen. Stroma was desmoplastic and showed foreign body giant cell reaction.
Figure 1: Scalp swelling with recent history of rapid growth

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Figure 2: Lobular well circumscribed proliferation of squamous cells with overlying normal appearing epidermis (H and E, ×10)

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Figure 3: Moderate-to-severe nuclear atypia in the squamous epithelial cells showing abrupt keratinisation without intervening granular layer (H and E, ×40)

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1.Kirkham N. Tumors and cysts of the epidermis. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, editors. Lever's Histopathology of the skin. 9 th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 814-6.  Back to cited text no. 1
    
2.Weedon D, editor. Skin pathology. 2 nd ed. Edinburgh: Churchill Livingstone; 2002. p.504-7.  Back to cited text no. 2
    
3.Klein W, Chan E, Seykora JT. Tumors of the epidermal appendages. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, editors. Lever's Histopathology of the skin. 9 th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 882-6.  Back to cited text no. 3
    
4.Kaddu S, Requena L. Malignant tumors with follicular differentiation. In: Le Boit PE, Burg G, Weedon D, Sarasin A. Editors. Pathology and genetics of skin tumours. Lyon: IARC press; 2006. p. 149-51.  Back to cited text no. 4
    
5.Kumar P, Chatura KR, Haravi RM, Chandra. Proliferating trichilemmal cyst mimicking squamous cell carcinoma. Indian J Dermatol Venereol Leprol 2000;66:149-50.  Back to cited text no. 5
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6.Trabelsi A, Stifa W, Gharbi O, Kanani N, Sriha B, Korbi S. Malignant proliferating trichilemmal tumour of the scalp: a case report. Dermatol Online J 2008;14(8):11.  Back to cited text no. 6
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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