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Year : 2012  |  Volume : 3  |  Issue : 1  |  Page : 80  

Angiolymphoid hyperplasia with eosinophilia


Department of Dermatology, Amrita Institute of Medical Sciences, Cochin, Kerala, India

Date of Web Publication3-Mar-2012

Correspondence Address:
Vinitha V Panicker
Department of Dermatology, Amrita Institute of Medical Sciences, Cochin, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.93481

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How to cite this article:
Panicker VV, Dhramaratnam AD, Kuruvilla J. Angiolymphoid hyperplasia with eosinophilia. Indian Dermatol Online J 2012;3:80

How to cite this URL:
Panicker VV, Dhramaratnam AD, Kuruvilla J. Angiolymphoid hyperplasia with eosinophilia. Indian Dermatol Online J [serial online] 2012 [cited 2019 Sep 18];3:80. Available from: http://www.idoj.in/text.asp?2012/3/1/80/93481

A 45 year old male presented with nodular lesions on the pinna for the past 2 years [Figure 1] Biopsy of the nodule showed prominent epitheloid endothelial cells and increased eosinophils and lymphoplasmacyte infiltrate around blood vessels [Figure 2] and [Figure 3]
Figure 1: Photograph showing multiple nodular lesions in the ear

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Figure 2: Histopathology photos showing prominent endothelial cells and increased lymphohistiocytic infiltrates around blood vessels (H and E, ×40)

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Figure 3: Increased lymphohistiocytic infiltrates and eosinophils around blood vessels (H and E, ×40)

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Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign disease with distinctive histopathological features. [1] It is characterized by single or multiple skin-colored or plum colored nodules or plaques especially in head and neck region. Kimura's disease, the close differential diagnosis, is characterized by larger lesions, subcutaneous nodules with involvement of salivary glands, and regional lymph nodes. [2] The smaller lesions of ALHE usually require no treatment and undergo spontaneous regression, but larger lesions require therapy. Surgical excision, intralesional corticosteroids, and pulsed dye laser therapy are the mainstay of treatment.

 
   References Top

1.Moesner J, Pallesen R, Sorensen B. Angiolymphoid hyperplasia with eosinophilia (Kimura's disease). Arch Dermatol 1981;117:6503.  Back to cited text no. 1
    
2.Churn SI, Ji HG. Kimura's disease and angiolymphoid hyperplasia with eosinophilia. J Am Acad Dermatol 1992;27:954-8.  Back to cited text no. 2
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]


This article has been cited by
1 Epidemiology and treatment of angiolymphoid hyperplasia with eosinophilia (ALHE): A systematic review
Brandon L. Adler,Aimee E. Krausz,Aurelia Minuti,Jonathan I. Silverberg,Hadar Lev-Tov
Journal of the American Academy of Dermatology. 2016; 74(3): 506
[Pubmed] | [DOI]



 

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