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CASE REPORT
Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 30-33

Aquagenic keratoderma. Two new case reports and a new hypothesis


1 Department of Dermatology and Venerology, Saint Kliment Ohridski University, University Hospital Lozenetz, Bulgaria
2 Department of Dermatology and Venerology, Medical University Sofia, Sofia, Bulgaria
3 Department of Dermatology, University Hospital of Coimbra, Coimbra, Portugal
4 Department of General and Clinical Pathology, Medical Faculty, Trakia University, Stara Zagora, Bulgaria
5 Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden Friedrichstadt, Dresden, Germany

Correspondence Address:
Uwe Wollina
Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden Friedrichstadt, Dresden, Germany

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.126025

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Aquagenic keratoderma has been described as a transient condition affecting predominantly young females and defined clinically by the appearance of palmar hyper-wrinkling accentuated after immersion in water. We present two new cases with aquagenic palmoplantar acrokeratoderma - a child and a young male. A significant clinical improvement was achieved after topical treatment with aluminum salts. Aquagenic palmar keratoderma may be a clue to cystic fibrosis in adolescents and young adults. We developed a new hypothesis on its pathogenesis.


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