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CASE REPORT
Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 69-71

Hyper IgE syndrome


Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China

Correspondence Address:
Songmei Geng
Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi wu Road 157, Xi'an, Shaanxi
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.126038

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Hyper IgE syndrome (HIES) is a rare disorder characterized by eczema, recurrent infections of the skin and lungs, typically with Staphylococcus aureus, Candida albicans and certain viruses, and elevated levels of serum IgE. Other clinical manifestations include characteristic facies (prominent forehead, broad nasal bridge and facial asymmetry), chronic eczematous dermatitis, retained primary dentition, recurrent pathological fractures, hyper-extensibility and scoliosis. The central nervous system (CNS) involvement in HIES has been rarely reported. Here we presented a case of HIES with rare associations of epilepsy in a young patient to raise awareness for this disorder.


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