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CASE REPORT
Year : 2014  |  Volume : 5  |  Issue : 2  |  Page : 193-195

Proteus syndrome: A rare cause of gigantic limb


1 Department of Medicine, Nil Ratan Sarkar Medical College, Kolkata, India
2 Department of Pharmacology, KPC Medical College, Kolkata, India
3 Midnapur Medical College and Hospital, Midnapur, India

Correspondence Address:
Nandini Chakrabarti
358, NSC Bose Road, Kolkata - 700 047
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.131108

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A congenital disorder with variable manifestations, including partial gigantism of the hands and feet with hypertrophy of soles, nevi, hemihypertrophy, gynecomastia, macrocephaly and other skull abnormalities, and abdominal lipomatosis. The cause is unknown, although a genetic origin, generally of autosomal-dominant transmission, has been conjectured. Symptoms can be treated, but there is no known cure. We present the case of a young male with grotesque overgrowth of the right lower limb, splenomegaly and multiple nevi. Angiography revealed venous malformation within the limb. The findings are in conformity to the criteria for the Proteus syndrome.


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