|SKINDIA QUIZ 19
|Year : 2015 | Volume
| Issue : 4 | Page : 302-303
SkIndia Quiz 19: Soft tumors in segmental fashion
Mahendra M Kura, Sumit Parsewar
Department of Dermatology, Venereology and Leprosy, Grant Medical College, Mumbai, Maharashtra, India
|Date of Web Publication||8-Jul-2015|
Dr. Mahendra M Kura
Department of Dermatology, Venereology and Leprosy, Grant Medical College, Sir Jamshedjee Jeejebhoy Hospital, Byculla, Mumbai - 400 008, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Kura MM, Parsewar S. SkIndia Quiz 19: Soft tumors in segmental fashion. Indian Dermatol Online J 2015;6:302-3
A 25-year-old male presented with multiple skin-colored to hyperpigmented, soft to firm raised lesions of varying sizes on the right side of the chest, back, and right upper extremity since six years. Lesions were tender to touch and had gradually increased in number and size to the present status. Family and personal history were noncontributory. Examination revealed multiple grouped, soft to firm, tender, skin-colored papules, and nodules ranging from 2 mm to 10 mm distributed on the right side of the chest extending from midline to anterior axillary line (T2-T6 dermatome) [Figure 1] and on the extensor aspect of the right upper extremity (C5-6 dermatome). [Figure 2]. Button-hole sign was negative and cold sensitivity was absent. Systemic clinical examination, urine microscopy, abdominal and pelvic sonography was normal. Histopathology showed a poorly demarcated tumor in the dermis around the hair follicle composed of interlacing bundles of spindle-shaped cells with elongated rounded nuclei and moderate cytoplasm [Figure 3].
|Figure 1: Cluster of skin-colored papules and nodules ranging from 2 mm to 1 cm, grouped on the right side of the chest in T2-T6 dermatome|
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|Figure 2: Similar multiple papules and nodules present on the extensor aspect of the right upper extremity, ranging from few millimeters to 2 cm|
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|Figure 3: A poorly demarcated tumor in the dermis around the hair follicle composed of interlacing bundles of spindle-shaped cells with elongated blunt nuclei and moderate cytoplasm suggestive of smooth muscle.(H and E, x40)|
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| What is the Diagnosis|| |
| References|| |
Malhotra P, Walia H, Singh A, Ramesh V. Leiomyoma cutis: A clinicopathological series of 37 cases. Indian J Dermatol 2010;55:337-41.
Rook AJ, Burns T, Breathnach S, Cox N, Griffiths C. editors. Textbook of Dermatology, Soft Tissue Tumors and Tumor Like Conditions. 8 th
ed, Vol 3. Oxford: Wiley-Blackwell science Ltd; 2010. 56. p. 54-6.
Lever WF, Elder, David E. Histopathology of skin. 9 th
ed.. Philadephia: Lippincott Williams and Wilkins company; 2005. p. 1078-82.
Braun SA, Hanneken S, Reifenberger J, Helbig D, Frank J. Hereditary cutaneous leiomyomatosis. Hautarzt 2012;63:276-8.
Tsoitis G, Kanitakis J, Papadimitriou C, Hatzibougias Y, Asvesti K, Happle R. Cutaneous leiomyomatosis with type 2 segmental involvement. J Dermatol 2001;28:251-5
Raymond VM, Herron CM, Giordano TJ, Gruber SB. Familial renal cancer as an indicator of hereditary leiomyomatosis and renal cell cancer syndrome. Fam Cancer 2012;11:115-21.
Kaliyadan F, Manoj J, Dharmaratnam AD, Multiple cutaneous leiomyomas: Pain relief with pulsed hyosine butyl bromide. Indian J Dermatol 2009;54:72-4.
Thompson JA Jr. Therapy for painful cutaneous leiomyomas. J Am Acad Dermatol 1985;13 (5 Pt 2):865-7.
Lang K, Reifenberger J, Ruzicka T, Megahed M. Type 1 segmental cutaneous leiomyomatosis. Clin Exp Dermatol 2002;27:649-50.
Rook AJ, Burns T, Breathnach S, Cox N, Griffiths C, editors. Textbook of Dermatology, Systemic Disease and Skin, 8 th
ed., Vol. 3. Oxford: Wiley-Blackwell Science Ltd; 2010. p. 29-62.
[Figure 1], [Figure 2], [Figure 3]