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CASE REPORT
Year : 2016  |  Volume : 7  |  Issue : 1  |  Page : 43-45

Treatment of refractory ulcerative necrobiosis lipoidica diabeticorum with oral thalidomide


Department of Dermatology and Venereology, Ashvini Rural Medical College, Solapur, Maharashtra, India

Correspondence Address:
Dr. Swapnil D Shah
441, Shukrawar Peth, Solapur - 413 002, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.174328

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Ulcerative necrobiosis lipoidica (NL) in diabetic patients is a rare, painful condition. It is a difficult-to-treat condition, impairing quality of life of patients. Although various drugs have been tried, none of them is consistently effective. Biologics in the form of TNF-alpha inhibitors show promising results in the treatment. But because of their high cost we chose thalidomide, which also has TNF-alpha inhibiting properties to successfully treat a long-standing case of ulcerative NL, which was refractory to various treatment modalities.


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