• Users Online: 1361
  • Print this page
  • Email this page
CASE REPORT
Year : 2016  |  Volume : 7  |  Issue : 2  |  Page : 93-95

Hepatitis B, interferon, and acne fulminans in a young girl


1 Department of Dermatology, Army College of Medical Sciences, Base Hospital, Delhi, India
2 Department of Pathology, Army College of Medical Sciences, Base Hospital, Delhi, India
3 Department of Gastroenterology, Army College of Medical Sciences, Base Hospital, Delhi, India

Correspondence Address:
Dr. Sandeep Arora
Department of Dermatology, Army College of Medical Sciences, Base Hospital, Delhi - 110 010
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.178080

Rights and Permissions

Acne fulminans (AF) is a very rare severe form of acne seen in young males, characterized by a sudden and explosive onset of hemorrhagic pustules and ulceration on the trunk, systemic features in the form of fever, polyarthropathy, malaise, erythema nodosum and painful osteolytic bone involvement with leukocytosis, and an elevated erythrocyte sedimentation rate. Conventional treatment of AF includes corticosteroids or immunosuppressive agents for the initial phase followed by isotretinoin. Active hepatitis B infection with a high viral load precludes the administration of any immunosuppressive drugs. We present the case of an 18-year-old girl with a history of occasional acne who presented with AF of sudden onset following administration of interferon-alpha-2a for her recently detected hepatitis B infection. Management of hepatitis B was withheld in view of her general condition. The patient was managed with low dose isotretinoin with subsidence of lesions. AF in a young female precipitated by interferon and its management with isotretinoin in the presence of active hepatitis B infection make the case unique.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2377    
    Printed10    
    Emailed0    
    PDF Downloaded205    
    Comments [Add]    

Recommend this journal