|LETTER TO THE EDITOR
|Year : 2016 | Volume
| Issue : 6 | Page : 538
Clinical study of cutaneous leishmaniasis in the Kashmir Valley
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, Baghdad University, Baghdad, Iraq
|Date of Web Publication||11-Nov-2016|
Mahmood Dhahir Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Al-Mendalawi MD. Clinical study of cutaneous leishmaniasis in the Kashmir Valley. Indian Dermatol Online J 2016;7:538
|How to cite this URL:|
Al-Mendalawi MD. Clinical study of cutaneous leishmaniasis in the Kashmir Valley. Indian Dermatol Online J [serial online] 2016 [cited 2020 Jul 2];7:538. Available from: http://www.idoj.in/text.asp?2016/7/6/538/193916
I read with interest the article by Wani et al. on the clinical study of cutaneous leishmaniasis (CL) in the Kashmir Valley. The authors stated that the migration of people from villages to small townships coupled with climatic changes over the last few years could be the contributing factors for the emergence of a new focus of CL in the Kashmir Valley. However, they did not address exactly how climatic changes could influence the development of that new phenomenon. It is obvious that CL is a vector-borne human disease caused by Leishmania major, a unicellular eukaryotic parasite transmitted by pool blood-feeding sandflies mainly to wild rodents, such as Psammomys obesus. The people who share the rodent and sandfly habitats can be subverted as both sandfly blood resource. Changes in climate could trigger the development of a new CL focus by the following mechanism. On one hand, the higher rainfall is expected to result in increased density of chenopods, a halophytic plant that constitutes the exclusive food of P. obesus. Consequently, following a high density of P. obesus, the pool of L. major transmissible from the rodents to blood-feeding female sandflies could lead to a higher probability of transmission to humans over the next season. On the other hand, climatic changes could increase minimum temperatures sufficiently and create conditions suitable for endemicity that did not previously exist. Moreover, temperatures above a critical range suppress CL incidence by limiting the vector's reproductive activity. I presume that the emergence of new foci of CL in India over the recent years ,, necessitates conduction of epidemiological and molecular studies to determine the reservoir of infection, the vector, and the strains of causative leishmania.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Wani GM, Ahmad SM, Khursheed B. Clinical study of cutaneous leishmaniasis in the Kashmir Valley. Indian Dermatol Online J 2015;6:387-92.
Toumi A, Chlif S, Bettaieb J, Ben Alaya N, Boukthir A, Ahmadi ZE, et al.
Temporal dynamics and impact of climate factors on the incidence of zoonotic cutaneous leishmaniasis in central Tunisia. PLoS Negl Trop Dis 2012;6:e1633.
Bounoua L, Kahime K, Houti L, Blakey T, Ebi KL, Zhang P, et al.
Linking climate to incidence of zoonotic cutaneous leishmaniasis (L. major
) in pre-Saharan North Africa. Int J Environ Res Public Health 2013;10:3172-91.
Sharma NL, Mahajan VK, Negi AK. Epidemiology of a new focus of localized cutaneous leishmaniasis in Himachal Pradesh. J Commun Dis 2005;37:275-9.
Rastogi V, Nirwan PS. Cutaneous leishmaniasis: An emerging infection in a non-endemic area and a brief update. Indian J Med Microbiol 2007;25:272-5.