|Year : 2017 | Volume
| Issue : 1 | Page : 70-72
SkIndia Quiz 33: Solitary pigmented plaque containing a blue-gray papule
Cody J Connor1, Brian L Swick2
1 Carver College of Medicine, University of Iowa, Iowa City Veterans Affairs Medical Center, Iowa, USA
2 Department of Dermatology and Pathology, University of Iowa, Iowa City Veterans Affairs Medical Center, Iowa, USA
|Date of Web Publication||20-Jan-2017|
Dr. Brian L Swick
Department of Dermatology, University of Iowa, 200 Hawkins Drive, 40025 PFP, Iowa City, Iowa - 52245
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Connor CJ, Swick BL. SkIndia Quiz 33: Solitary pigmented plaque containing a blue-gray papule. Indian Dermatol Online J 2017;8:70-2
|How to cite this URL:|
Connor CJ, Swick BL. SkIndia Quiz 33: Solitary pigmented plaque containing a blue-gray papule. Indian Dermatol Online J [serial online] 2017 [cited 2020 Sep 27];8:70-2. Available from: http://www.idoj.in/text.asp?2017/8/1/70/193928
A 35-year-old woman presented with a new dark papule that had arose within a previously stable tan plaque on her right thigh. There was no history of itching or bleeding from the lesion. Her past medical and family history were unremarkable. On examination, there was a 1.1 cm sharply demarcated tan plaque on the right anterior thigh containing an eccentric blue-gray papule [Figure 1].
|Figure 1: Tan plaque containing an eccentric blue-gray papule on the right anterior thigh|
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Low-power histopathologic examination revealed a nested proliferation of cytologically bland appearing melanocytes focally along the dermoepidermal junction and more extensively in the dermis with a second population of pigmented epithelioid appearing melanocytes with surrounding melanophages in the upper reticular dermis [Figure 2]. High-power viewing confirmed the presence of two populations of melanocytes; the first was the small amelanotic population and the second consisted of localized nests of epithelioid melanocytes with conspicuous cytoplasmic melanization. There were prominent pigmented melanophages [Figure 3].
|Figure 2: Compound melanocytic nevus with a focus of pigmented epithelioid appearing melanocytes with surrounding melanophages (H and E, original magnification ×100)|
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|Figure 3: Focus of pigmented epithelioid appearing melanocytes with enlarged atypical appearing nuclei and surrounding pigmented melanophages with adjacent nests of smaller nonpigmented type B melanocytes (H and E, original magnification ×400)|
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| What Is the Diagnosis?|| |
- Cellular blue nevus
- Clonal nevus (inverted type A nevus)
- Common blue nevus
- Deep penetrating nevus
- Epithelioid blue nevus
| References|| |
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[Figure 1], [Figure 2], [Figure 3]