|Year : 2017 | Volume
| Issue : 2 | Page : 155-156
SkIndia quiz 35: A girl with multiple papules
Siddhi Gaurish Sinai Khandeparkar1, Maithili M Kulkarni1, Sanjay Deshmukh1, Yuvraj E More2
1 Department of Pathology, Shrimati Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
2 Department of Dermatology, Shrimati Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
|Date of Web Publication||16-Mar-2017|
Siddhi Gaurish Sinai Khandeparkar
Shrimati Kashibai Navale Medical College and General Hospital, Narhe, Off Pune-Mumbai, Pune - 411 041, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Sinai Khandeparkar SG, Kulkarni MM, Deshmukh S, More YE. SkIndia quiz 35: A girl with multiple papules. Indian Dermatol Online J 2017;8:155-6
|How to cite this URL:|
Sinai Khandeparkar SG, Kulkarni MM, Deshmukh S, More YE. SkIndia quiz 35: A girl with multiple papules. Indian Dermatol Online J [serial online] 2017 [cited 2017 May 1];8:155-6. Available from: http://www.idoj.in/text.asp?2017/8/2/155/198810
A two-and-a-half-year-old female child presented with multiple round to oval, reddish-brown, slightly elevated, asymptomatic lesions since 3 months of age over her face and upper limbs. The lesions were initially few in number and gradually increased over a period of one year. On clinical examination, multiple, well-defined, bilaterally symmetrical, skin colored to pink to reddish-brown macules and papules of about 0.5 × 0.5 cm were seen over the face [Figure 1], ears, upper limbs, and distal aspect of lower limbs. Her family history, general and systemic examination findings were normal. Routine laboratory investigations such as complete blood count, liver and renal function tests, and lipid profile were normal. A skin biopsy was taken from the papule over the arm. On histopathological examination, the epidermis showed mild hyperkeratosis, and the upper dermis showed collections of multinucleated giant cells with multiple small cytoplasmic vacuolations, of Touton type with a few collagen bundles in between. Mild chronic lymphoplasmacytic infiltrate was noted in perivascular and periadnexal areas [Figure 2].
|Figure 1: Clinical photograph: Symmetrically distributed skin colored to pinkish to reddish brown macules and few papules of about 0.5 × 0.5cm seen over face|
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|Figure 2: Photomicrograph of tumor: upper dermis showing collections of Touton type of giant cells (H and E, ×400)|
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| What Is the Diagnosis?|| |
| References|| |
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Aburezq H, Jaeger M, Iyengar P, Zuker R. Juvenile xanthogranuloma of the nose. Can J Plast Surg 2004;12:198-200.
Cypel TK, Zuker RM. Juvenile xanthogranuloma: Case report and review of the literature. Can J Plast Surg 2008;16:175-7.
[Figure 1], [Figure 2], [Figure 3]