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SKINDIA QUIZ
Year : 2017  |  Volume : 8  |  Issue : 4  |  Page : 297-299  

SkIndia Quiz 39: Pebbly flexural skin in a young female


Department of Dermatology, Venereology and Leprology, R.N.T Medical College, Udaipur, Rajasthan, India

Date of Web Publication5-Jul-2017

Correspondence Address:
Lalit K Gupta
Department of Dermatology, Venereology and Leprology, R.N.T Medical College, Udaipur - 313001, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_149_16

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How to cite this article:
Gupta LK, Beniwal R, Bharti G, Khare AK, Mittal A, Mehta S, Balai M. SkIndia Quiz 39: Pebbly flexural skin in a young female. Indian Dermatol Online J 2017;8:297-9

How to cite this URL:
Gupta LK, Beniwal R, Bharti G, Khare AK, Mittal A, Mehta S, Balai M. SkIndia Quiz 39: Pebbly flexural skin in a young female. Indian Dermatol Online J [serial online] 2017 [cited 2019 Dec 9];8:297-9. Available from: http://www.idoj.in/text.asp?2017/8/4/297/206145

A 23-year-old female patient presented with a 5-year history of 1–2 mm skin-colored to yellowish, linearly arranged non-scaly papules and plaques over the axillae and lateral aspects of the neck [Figure 1]a,[Figure 1]b,[Figure 1]c. The lesions were gradually progressive and associated with increased skin laxity. Mucosae appeared normal. She had no systemic complaints. None of the family members had a similar lesion.
Figure 1: (a-c) Skin-colored to yellowish, discrete, and confluent papules and plaques over the axillae and neck

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Routine laboratory investigations, radiography of the chest, echocardiography and ultrasonography of the abdomen were normal. Ophthalmological examination revealed “peau d' orange” like mottling in the macular area with multiple spot-like “comet tail lesions” in chorioretinal region. Skin biopsy taken from the axilla revealed features as shown in [Figure 2]. Special stain for elastic tissue was positive [Figure 3]a and [Figure 3]b.
Figure 2: Hematoxylin and eosin stain showing clumped and degenerate elastic fibres in the dermis (×10)

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Figure 3: (a and b) Swollen and irregularly clumped elastic fibres stained black with VVG stain (×40 and ×100)

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   Question Top


What is your diagnosis?



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   References Top

1.
Moreira AP, Feijó FS, Pinto JM, Martinelli IL, Rochael MC. Pseudoxanthoma elasticum. Dermatology Online J 2009;15:7.  Back to cited text no. 1
    
2.
Gonzalez ME, Votava HJ, Lipkin G, Sanchez M. Pseudoxanthoma elasticum. Dermatol Online J 2009;15:17.  Back to cited text no. 2
    
3.
Kumar P, Sivasubramanian A, Vadivel S, Krishnaswamy M. Pseudoxanthoma elasticum with periumbilical perforation in a Nullipara. Indian J Dermatol 2012;57:210-2.  Back to cited text no. 3
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4.
Burrows NP, Lovell CR. Disorders of connective tissue. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's textbook of dermatology. 8th ed. UK: Wiley-Blackwell Publishing Ltd; 2010. p. 46.21-6.  Back to cited text no. 4
    
5.
Hemmady K, Tambe S, Jerajani HR. Asymptomatic esophageal varices in a case of pseudoxanthoma elasticum. Indian Dermatol Online J 2015;6(Suppl S1):65-6.  Back to cited text no. 5
    
6.
Mehta B, Amladi S, Nayak C, Savant S. An unusual periumbilical plaque. Indian J Dermatol Venereol Leprol 2008;74:697-8.  Back to cited text no. 6
[PUBMED]  [Full text]  
7.
Christen-Zäch S, Huber M, Struk B, Lindpaintner K, Munier F, Panizzon RG, et al. Pseudoxanthoma elasticum: Evaluation of diagnostic criteria based on molecular data. Br J Dermatol 2006;55:89-93.  Back to cited text no. 7
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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