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SKINDIA QUIZ
Year : 2017  |  Volume : 8  |  Issue : 4  |  Page : 300-301  

SkIndia Quiz 40: Papulosquamous papules and plaques covered with hemorrhagic crusts on the anterior trunk


1 Department of Dermatology, Dicle University Medical Faculty, Diyarbakır, Turkey
2 Department of Dermatology, Erciş State Hospital, Van, Turkey
3 Department of Pathology, Dicle University Medical Faculty, Diyarbakır, Turkey

Date of Web Publication5-Jul-2017

Correspondence Address:
Isa An
Department of Dermatology, Dicle University Medical Faculty, Diyarbakır
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_349_16

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How to cite this article:
An I, Yüce GA, Ucmak D, Ibiloglu I. SkIndia Quiz 40: Papulosquamous papules and plaques covered with hemorrhagic crusts on the anterior trunk. Indian Dermatol Online J 2017;8:300-1

How to cite this URL:
An I, Yüce GA, Ucmak D, Ibiloglu I. SkIndia Quiz 40: Papulosquamous papules and plaques covered with hemorrhagic crusts on the anterior trunk. Indian Dermatol Online J [serial online] 2017 [cited 2020 Aug 13];8:300-1. Available from: http://www.idoj.in/text.asp?2017/8/4/300/206146

A 1-year-old girl was brought to our clinic by her parents with the complaint of papulosquamous lesions covered with hemorrhagic crusts on the anterior trunk. The patient had developed erythematous squamous plaques on the scalp, inguinal region, and the face at the age of 3 months. The patient was given a therapy of topical steroids and oral antihistaminic drugs. However, the lesions did not resolve. Dermatological examination revealed papulosquamous papules and plaques covered with hemorrhagic crusts on the scalp, skin folds, and on the anterior trunk [Figure 1]. The patient had a history of frequent otitis media. Hematological investigations indicated presence of pancytopenia. Ultrasonography showed lymphadenopathy in the cervical region. Histopathologic evaluation of the lesions on the anterior trunk showed mononuclear cell infiltration in the interstitial region in the papillary and reticular dermis and histiocytic cell infiltration in the papillary dermis [Figure 2]a. Immunohistochemical analysis indicated CD1a surface antigen (+) and S100 protein (+) [Figure 2]b and [Figure 2]c.
Figure 1: Dermatological examination revealed papulosquamous papules and plaques covered with hemorrhagic crusts on the scalp, skin folds, and on the anterior trunk

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Figure 2: (a) Mononuclear cell infiltration in the interstitial region in the papillary and reticular dermis and histiocytic cell infiltration in the papillary dermis (H and E, ×200). (b) Immunohistochemical analysis indicated CD1a surface antigen (+) (×200). (c) Immunohistochemical analysis indicated S100 protein (+) (×200)

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   References Top

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2.
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Satter EK, High WA. Langerhans cell histiocytosis: A review of the current recommendations of the Histiocyte Society. Pediatr Dermatol 2008;25:291-5.  Back to cited text no. 3
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Arico M, Egeler RM. Clinical aspects of Langerhans cell histiocytosis. Hematol Oncol Clin North Am 1998;12:24759.  Back to cited text no. 4
    
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Newman B, Hu W, Nigro K, Gilliam AC. Aggressive histiocytic disorders that can involve the skin. J Am Acad Dermatol 2007;56:302-16.  Back to cited text no. 5
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