• Users Online: 330
  • Print this page
  • Email this page
Year : 2017  |  Volume : 8  |  Issue : 6  |  Page : 468-470

Mean platelet volume: A reliable marker of inflammation in recurrent apthous stomatitis and behçet disease?

1 Department of Dermatology, Faculty of Medicine, Hitit University; Beekeeping and Bee Products Application and Research Center, Hitit University, Çorum, Turkey
2 Clinic of Internal Medicine, Çankiri State Hospital, Çankiri, Turkey
3 Department of Dermatology, Faculty of Medicine, Hitit University, Çorum, Turkey

Correspondence Address:
Engin Senel
Department of Dermatology, Faculty of Medicine, Hitit University, Çorum
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/idoj.IDOJ_405_16

Rights and Permissions

Background: Mean platelet volume (MPV) is an indicator of platelet activation and aggregation. MPV has been found to be related with the inflammation of certain disorders in recent studies. Aims: We sought to investigate whether MPV could be an indicator of inflammation in patients with Behçet disease (BD) and recurrent apthous stomatitis (RAS). Materials and Methods: Our study was designed as a retrospective case-control study and data was retrieved from our institutional database. We randomly generated a total of three study groups from our clinical archive. All controls were sex and age-matched and randomly selected by computer. Eighty-five patients with BD, 82 patients with RAS, and 721 healthy controls were included for the study design. We compared mean MPV values in the patient groups and controls. Results: We found no difference in the mean MPV value between BD group and BD-control group. The mean MPV value was significantly higher in patients with RAS than that in the RAS-control group (9.11 ± 1.01 fL vs. 8.76 ± 1.15 fL, P = 0.045). There was no difference in mean MPV level between BD and RAS group. Conclusion: The association between MPV and inflammatory skin diseases such as BD and RAS should be investigated prospectively in case-control studies. Limitations: Retrospective study design.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded149    
    Comments [Add]    

Recommend this journal