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SKINDIA QUIZ
Year : 2017  |  Volume : 8  |  Issue : 6  |  Page : 518-519  

SkIndia quiz 42: Multiple slow-growing papulonodular lesions over the nose


1 Department of Dermatology, Venereology and Leprosy, Rajah Muthiah Medical College Hospital, Chidambaram, Tamil Nadu, India
2 Department of Pathology, Rajah Muthiah Medical College Hospital, Chidambaram, Tamil Nadu, India

Date of Web Publication14-Nov-2017

Correspondence Address:
P. V. S. Prasad
Department of Dermatology, Venereology and Leprosy, Rajah Muthiah Medical College and Hospital, Annamalai Nagar, Chidambaram - 608 002, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.214951

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How to cite this article:
Kamini C R, Prasad P, Kaviarasan P K, Viswanathan P. SkIndia quiz 42: Multiple slow-growing papulonodular lesions over the nose. Indian Dermatol Online J 2017;8:518-9

How to cite this URL:
Kamini C R, Prasad P, Kaviarasan P K, Viswanathan P. SkIndia quiz 42: Multiple slow-growing papulonodular lesions over the nose. Indian Dermatol Online J [serial online] 2017 [cited 2019 Jun 17];8:518-9. Available from: http://www.idoj.in/text.asp?2017/8/6/518/214951



A 67-year-old lady presented with multiple, slow-growing, pinkish, smooth surfaced, sessile, coalescing nodules of size 0.8 × 0.6 cm and few discrete papules measuring about 0.5 × 0.3 cm over the bridge of nose for 6 years [Figure 1]. The papulonodular lesions were firm, nontender, and without any attachment to the underlying structures. Family history was unremarkable. Excisional biopsy of the discrete papules and a core biopsy from a section of the coalesced nodular lesion was done and sent for microscopic examination.
Figure 1: Multiple coalescing nodules and discrete papules over the nose

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Histopathology revealed islands of epithelial cells arranged in the upper dermis under low power view [Figure 2]. Each lobule was composed of peripheral palisading of dark basaloid cells and relatively paler cells in the center. The tumor islands were surrounded by a basement membrane such as hyaline eosinophilic structure, which is appreciated under higher magnification [Figure 3].
Figure 2: Photomicrograph showing islands of epithelial cells in the upper dermis (H and E, ×10)

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Figure 3: Photomicrograph showing epithelial lobules containing inner cells with pale nuclei and peripheral cells with dark nuclei (H and E, ×40)

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   Question Top


What is your diagnosis?



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   References Top

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Alsaad KO, Obaidat NA, Ghazarian D. Skin adnexal neoplasms - part 1: An approach to tumours of the pilosebaceous unit. J Clin Pathol 2007;60:129-44.  Back to cited text no. 1
    
2.
Raman M, Singh N. Familial multiple cylindromas. Indian J Dermatol Venereol Leprol 1991;57:104-6.  Back to cited text no. 2
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3.
Kim C, Kovich OI, Dosik J. Brooke–Spiegler syndrome. Dermatol Online J 2007;13:10.  Back to cited text no. 3
    
4.
Mahmoud A, Hill DH, O'Sullivan MJ, Bennett MW. Cylindroma of the breast: A case report and review of the literature. Diagn Pathol 2009;4:30.  Back to cited text no. 4
    
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Bansal C, Batra M, Lal N, Srivastava AN. Solitary Cylindroma with Malignant Transformation. Indian J Dermatol 2012;57:141-3.  Back to cited text no. 5
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    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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