• Users Online: 5087
  • Print this page
  • Email this page


 
  Table of Contents  
SKINDIA QUIZ
Year : 2018  |  Volume : 9  |  Issue : 2  |  Page : 133-134  

SkIndia Quiz 44: Growing asymptomatic nodule on the ear


1 Orange Park Medical Center Department of Dermatology, Orange Park, USA
2 Department of Dermatopathology, Aurora Diagnostics Bernhardt Laboratories, Jacksonviile, Florida, USA

Date of Web Publication19-Mar-2018

Correspondence Address:
Alyssa Miceli
Park Avenue Dermatology, 906 Park Avenue, Orange Park, Florida - 32073
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_141_17

Rights and Permissions

How to cite this article:
Miceli A, Church A, Ferrer-Bruker S. SkIndia Quiz 44: Growing asymptomatic nodule on the ear. Indian Dermatol Online J 2018;9:133-4

How to cite this URL:
Miceli A, Church A, Ferrer-Bruker S. SkIndia Quiz 44: Growing asymptomatic nodule on the ear. Indian Dermatol Online J [serial online] 2018 [cited 2020 Feb 29];9:133-4. Available from: http://www.idoj.in/text.asp?2018/9/2/133/223756



A 56-year-old Caucasian woman presented with a lesion on the right ear of 5-year duration. The site had undergone incision and drainage with no expression of contents followed by a complete excisional punch biopsy 4 years prior to presentation. The patient now presented with recurrence of the lesion, which she reported had been growing in size. Despite its growth, the lesion remained asymptomatic. Physical examination revealed a dermal nodule with a bluish hue and visible telangiectasias on the root of right ear, measuring 1.7 cm in size [Figure 1]. Histopathologic evaluation of a biopsy revealed a dermal-based, well-circumscribed lobulated tumor island composed of basophilic cells with little cytoplasm [Figure 2]a. Higher magnification showed two types of tumor cells – small, dark basaloid cells with scant cytoplasm and small nuclei and slightly larger cells with a more open nuclear chromatin pattern [Figure 2]b. The larger cells surrounded areas of focal ductal differentiation. No atypical features were identified.
Figure 1: Dermal nodule with a bluish hue and visible telangiectases on the right root of the ear

Click here to view
Figure 2: (a) Well-circumscribed lobulated tumor island composed of basophilic cells with little cytoplasm (H and E, original magnification ×20). (b) Close inspection revealing two cell types – small, dark basaloid cells with scant cytoplasm and slightly larger cells with a more open nuclear chromatin pattern. Scattered lymphocytes and hyaline deposits are noted in the tumor nodules (H and E, original magnification ×200)

Click here to view



   Question Top


What is your diagnosis?



Click here to view answer. View Answer


 
   References Top

1.
Kerstein DW, Helwig EB. Eccrine spiradenoma. AMA Arch Derm 1956;73:199-227.  Back to cited text no. 1
    
2.
Bumgardner AC, Hsu S, Nunez-Gussman JK, Schwartz MR. Trichoepitheliomas and eccrine spiradenomas with spiradenoma/cylindroma overlap. Int J Dermatol 2005;44:415-7.  Back to cited text no. 2
    
3.
Hashimoto K, Lever WF. Histogenesis of skin appendage tumors. Arch Dermatol 1969;100:356-69.  Back to cited text no. 3
    
4.
Meybehm M, Fischer HP. Spiradenoma and dermal cylindroma: Comparative immunohistochemical analysis and histogenetic considerations. Am J Dermatopathol 1997;19:154-61.  Back to cited text no. 4
    
5.
Im M, Kim DH, Park JS, Chung H, Lee Y, Kim CD, et al. Alteration of the β-catenin pathway in spiradenoma. J Cutan Pathol 2011;38:657-62.  Back to cited text no. 5
    
6.
Rajan N, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A. Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression. J Cutan Pathol 2011;224:309-21.  Back to cited text no. 6
    
7.
Granter SR, Seeger K, Calonje E, Busam K, McKee PH. Malignant eccrine spiradenoma (spiradenocarcinoma): A clinicopathologic study of 12 cases. Am J Dermatopathol 2000;22:97-103.  Back to cited text no. 7
    


    Figures

  [Figure 1], [Figure 2]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
   Question
   Answer
   Discussion
    References
    Article Figures

 Article Access Statistics
    Viewed1171    
    Printed23    
    Emailed0    
    PDF Downloaded133    
    Comments [Add]    

Recommend this journal