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ORIGINAL ARTICLE
Year : 2019  |  Volume : 10  |  Issue : 1  |  Page : 13-18

A 10-year retrospective descriptive study on pure neuritic leprosy from a tertiary referral centre


1 Department of General Medicine, Government Medical College, Kozhikode, Kerala, India
2 Department of Dermatology and Venereology, Government Medical College, Kozhikode, Kerala, India
3 Department of Community Medicine, Government Medical College, Kozhikode, Kerala, India
4 Health Services Department, Koyilandi Taluk Hospital, Koyilandy, Kerala, India

Correspondence Address:
Sarita Sasidharanpillai
“Rohini,” Girish Nagar, Nallalam Post, Kozhikode - 673 027, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_118_18

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Context: Pure neuritic leprosy is a risk factor for grade 2 disability owing to the early nerve damage. Aims: To study the clinical patterns of neuritic leprosy, to determine the percentage of patients manifesting grade 2 disability at the time of diagnosis and to identify any risk factors for the same. Settings and Design: Retrospective descriptive study from previous case records of pure neuritic leprosy patients who attended a tertiary centre from 1st July 2007 to 30th June 2017. Subjects and Methods: Data on patients who satisfied the World Health Organization (WHO) cardinal criteria for diagnosis of leprosy, who had no skin lesion of leprosy and had acid-fast bacilli negative status on skin smears were collected using a pre-set proforma. Statistical Analysis Used: The Chi-square test was used to assess statistical significance and logistic regression model was applied to avoid the effects of confounding factors. Results: A diagnostic delay of >1 year was observed in 44% patients. At the time of diagnosis, grade 2 disability was documented in 60 (80%) of patients. No statistically significant risk factor was identified for grade 2 disability. Limitations: Retrospective nature and the study conducted in a tertiary care centre not reflecting the status in the community were the limitations. Conclusions: Grade 2 disability noted in 80% of patients points to the inherent nature of disease to cause early nerve damage. Diagnostic delay of >1 year documented in 44% of patients underscores the diagnostic challenges in the absence of skin lesions.


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