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DERMATOLOGY PEARLS
Year : 2020  |  Volume : 11  |  Issue : 1  |  Page : 119  

An easy, cheap, and user-friendly technique for topical immunotherapy with diphencyprone: Cotton tip injector technique


Marmara University, Department of Dermatology, Istanbul, Turkey

Date of Web Publication13-Jan-2020

Correspondence Address:
Gizem Demir
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi Dermatoloji Anabilim Dali Fevzi Cakmak Mah, Mimar Sinan Cad. No:41 34899 Pendik, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_97_19

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How to cite this article:
Kaptanoglu AF, Özgen Z, Demir G, Cömert E. An easy, cheap, and user-friendly technique for topical immunotherapy with diphencyprone: Cotton tip injector technique. Indian Dermatol Online J 2020;11:119

How to cite this URL:
Kaptanoglu AF, Özgen Z, Demir G, Cömert E. An easy, cheap, and user-friendly technique for topical immunotherapy with diphencyprone: Cotton tip injector technique. Indian Dermatol Online J [serial online] 2020 [cited 2020 Jul 3];11:119. Available from: http://www.idoj.in/text.asp?2020/11/1/119/275690



Topical immunotherapy with diphencyprone (DPCP) is an effective treatment option in alopecia areata. This treatment should be performed very carefully following a standard protocol application.

Health care professionals are advised to take proper precautions. The solution is applied on the scalp with a cotton swab. Muthuvel recommends“fast applications” to cover entire scalp before acetone starts evaporating.[1] Evaporation of acetone can cause a change in the concentration of the solution, which may lead to more irritation, swelling, and disturbance of the treatment protocol. In our technique, the planned concentration of DPCP in acetone is drawn into the syringe to avoid evaporation. The needle of syringe is removed and a shortened cotton tip is placed to the endof the syringe. With the help of gravity and capillary flow principle, the DPCP solution slowly moves to the cotton tip only allowing dampening by slightly pressing the syringe without spilling [Figure 1]a and [Figure 1]b. With this application technique, DPCP solution can be easily and safely applied on affected areas [Figure 1]c.
Figure 1: ( a) Cotton tip applicator with hollow tube. (b) Syringe is filled with solution and instead of the needle shortened cotton tip is inserted in to the syringe. (c) A safe closed system with a soft application tip is ready to use

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There are many solutions in dermatology practice that can be applied with using only a cotton tipapplicator. Cotton tip applicator is a multipurpose and cost-effective tool in dermatology.[2] However, some solutions like DPCP are dissolved in acetone and changes in concentrations level due to evaporation is an obstacle to overcome. Here, the cotton tip injector technique is described. As it minimizes the evaporation surface compared to applications from a petri box, it helps the physician to ensure the concentration of DPCP in a closed system during application. We suggest that this easy, low-cost, and user-friendly technique can be useful to reduce the side effects and improve patient compliance during DPCP treatment.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Kumaresan M. Practicality in using diphenyl cyclo propenone for alopecia areata. Int J Trichology 2011;3:96-7.  Back to cited text no. 1
    
2.
Orengo I, Salasche SJ. Surgical pearl: The cotton-tipped applicator—The ever-ready, multipurpose superstar. J Am Acad Dermatol 1994;31:658-60.  Back to cited text no. 2
    


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