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Year : 2020  |  Volume : 11  |  Issue : 1  |  Page : 83-86

An exuberant case of necrobiotic xanthogranuloma

1 Department of Dermatology and Venereology, Centro Hospitalar e Universitário de São João EPE, Porto, Portugal
2 Department of Pathology, Centro Hospitalar e Universitário de São João EPE, Porto, Portugal

Correspondence Address:
Sofia Lopes
Alameda Hêrnani Monteiro, 4200-319 Porto
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/idoj.IDOJ_74_19

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Necrobiotic xanthogranuloma (NXG) is a rare form of inflammatory granulomatous disease of the skin characterized by the presence of pruritic to painful lesions, generally located in the periorbital area, although trunk and proximal extremities may also be involved. We report a case of a 69-year-old male patient with extensive involvement of the trunk, upper and lower extremities, and an associated gamma monoclonal gammopathy. The skin biopsy was consistent with the diagnosis of NXG. Necrobiosis lipoidica and granuloma annulare were the major differential diagnosis in this case. We highlight the importance of searching for clinical and histological features that may differentiate these entities, which is crucial to select an adequate therapeutic and surveillance strategy.

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