• Users Online: 465
  • Print this page
  • Email this page
Year : 2020  |  Volume : 11  |  Issue : 2  |  Page : 158-166

Cardiovascular and metabolic risk assessment in patients with lichen planus: A tertiary care hospital-based study from Northern India

1 Department of Dermatology, Government Medical College, Jammu, Jammu and Kashmir, India
2 Dermatology Division, Maccabi Healthcare Services, Israel
3 Centre for Health Equity Training, Research and Evaluation (CHETRE), UNSW, Sydney, Australia
4 Department of Community Medicine, Jawahar Lal Nehru Medical College, AMU, Aligarh, Uttar Pradesh, India
5 Department of Dermatology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India

Correspondence Address:
Sabha Mushtaq
Department of Dermatology, Government Medical College, Jammu - 180 001, Jammu and Kashmir (J and K)
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/idoj.IDOJ_228_19

Rights and Permissions

Background: The association between lichen planus (LP) and cardiovascular disease (CVD) risk factors has been demonstrated in previous reports. However, the evidence of CVD risk factors in Indian patients with LP is limited. Objective: To compare CVD risk factors in LP patients and healthy controls. Methods: We performed a cross-sectional study on 122 subjects, 61 LP patients, and 61 controls who visited the outpatient clinic of the dermatology department of a tertiary care hospital. Patients with skin diseases known to be associated with CV risk, pregnant, and lactating women were excluded from the study. CVD risk factors were compared between LP cases and controls using anthropometric measures, hemodynamic and metabolic parameters, and inflammatory marker (ESR). Results: The proportion of metabolic syndrome (MS) was significantly higher in LP patients than the controls (29.5% vs. 9.8%, odds ratio [OR] 3.83; 95% confidence interval [CI] 1.40–10.50; P = 0.006). The proportion of dyslipidemia was also significantly higher in LP patients (70.5% vs. 42.6%; P = 0.002). LP patients had a high proportion of obesity (P = 0.004), hypertension (P = 0.004), impaired fasting glucose (P = 0.025), and raised ESR (P = 0.006) as compared to controls. A multivariate regression model demonstrated that dyslipidemia and obesity were significantly associated with LP even after controlling for confounders such as age, gender, sedentarism, dietary habits, alcohol, and impaired fasting glucose. There was no significant association between the extent of LP and the proportion of MS or dyslipidemia. Conclusion: The present study found a significant association of LP with individual CVD risk factors as well as MS.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded417    
    Comments [Add]    

Recommend this journal