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CASE REPORT
Year : 2020  |  Volume : 11  |  Issue : 4  |  Page : 607-611

Complete remission in a patient with treatment refractory bullous pemphigoid after a single dose of omalizumab


1 Department of Dermatology, Venereology and Leprology, Dr. RML Hospital and PGIMER, New Delhi, India
2 Department of Pathology, Dr. RML Hospital and PGIMER, New Delhi, India

Correspondence Address:
Kabir Sardana
Room No. 108, Dermatology OPD, Dr. RML Hospital & ABVIMS, Baba Kharak Singh Marg, New Delhi - 110 001
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.IDOJ_438_19

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Bullous pemphigoid (BP) is an autoimmune disorder known to be mediated by immunoglobulin G (IgG) autoantibodies. The role of immunoglobulin E (IgE) antibodies is being investigated as their presence has been described in severe cases. Herein, we report a patient of BP who was refractory to most conventional agents and developed hypotension after rituximab but achieved lasting remission after a single dose of the anti-IgE monoclonal antibody omalizumab.


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