Indian Dermatology Online Journal

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 5  |  Issue : 2  |  Page : 128--131

Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris


Sanjiv V Choudhary, Taru Aghi, Shazia Bisati 
 Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India

Correspondence Address:
Sanjiv V Choudhary
28 Modern Nagpur Society, Chatrapati Nagar, Nagpur - 440 015, Maharashtra
India

Aims: To study and compare the efficacy and safety of topical terbinafine hydrochloride 1% cream and eberconazole nitrate 1% cream in localized tinea corporis and cruris. Methods and Materials: Patients were randomized after considering various inclusion and exclusion criteria into two groups. Group A (treated with terbinafine 1% cream for 3 weeks) and group B (treated with eberconazole 1% cream for 3 weeks). The sample size was of 30 patients with 15 patients in each group. Assessment of clinical improvement, KOH mount and culture was done weekly up to 3 weeks to assess complete cure. Results: On comparison between the two groups, it was observed that eberconazole nitrate 1% cream was as effective as terbinafine hydrochloride 1% cream at the end of first (Non-sisgnificant (NS); P = 0.608, 1.00), second (NS; P = 0.291,0.55), and third (P = 1.00, 1.00) weeks with statistically nonsignificant clinical and mycological values. In both the groups, clinically no significant local side effects were noticed. Conclusions: The newer fungistatic eberconazole nitrate 1% cream was as effective as the fungicidal terbinafine hydrochloride 1% cream. Both the drugs showed good tolerability with no adverse effects.


How to cite this article:
Choudhary SV, Aghi T, Bisati S. Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris.Indian Dermatol Online J 2014;5:128-131


How to cite this URL:
Choudhary SV, Aghi T, Bisati S. Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris. Indian Dermatol Online J [serial online] 2014 [cited 2019 Oct 15 ];5:128-131
Available from: http://www.idoj.in/article.asp?issn=2229-5178;year=2014;volume=5;issue=2;spage=128;epage=131;aulast=Choudhary;type=0