Indian Dermatology Online Journal

: 2015  |  Volume : 6  |  Issue : 1  |  Page : 58--59

SkIndia Quiz 16: A girl with a grotesque face

Sudip Das 
 Department of Dermatology and Venerology, NRS Medical College and Hospital, Kolkata, India

Correspondence Address:
Sudip Das
P103 Bosenagore Madhyamgram 24 Parganas (n), Kolkata - 700 129

How to cite this article:
Das S. SkIndia Quiz 16: A girl with a grotesque face.Indian Dermatol Online J 2015;6:58-59

How to cite this URL:
Das S. SkIndia Quiz 16: A girl with a grotesque face. Indian Dermatol Online J [serial online] 2015 [cited 2020 May 28 ];6:58-59
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A 10-year-old girl reported with large tumorous masses on the face for about 6 months [Figure 1]. These started as small eruptions. Few of them were ulcerated and secondarily infected. The patient was HIV negative and CD4 cell count was 830/cu mm. Histopathology from a smaller lesion showed hypertrophic lobular epidermis and few epidermal cells were hugely distended with intracytoplasmic inclusion bodies [Figure 2]. {Figure 1}{Figure 2}

 What is the diagnosis?

 View Answer


Giant molluscum in an immuocompetent individual.


Molluscum contagiosum (MC) is a common viral infection appearing as solitary or a small group of characteristic flesh colored, translucent papules on face, trunk, genitalia, and other body parts. Increased number of lesions may be seen in malignancies, immunosuppresion due to disease or drugs. [1] In patients with acquired immune deficiency syndrome, [2] the lesions affect the eyelids, conjunctiva, can be of huge size (10-15 mm) and number and resistant to therapy. MCs of such number, size, and secondary changes are unusual in the immunocompetent individual. Confirmation is by demonstrating enlarged epithelial cell with intracytoplasmic molluscum bodies. Differential diagnoses include folliculitis, warts, keratoacanthoma or cryptococcosis. Treatment modalities include cyotherapy, extirpation followed by cauterization of the base, or chemical cautery. In our patient, surgical excision combined with electro cautery was performed resulting in complete clearance and cosmetic improvement. [Figure 3].{Figure 3}


1Kumar P, Chatura KR, Jagannath VK, Hara. Giant molluscum contagiosum in an infant. Indian J Dermatol Venereol Leprol 1999;65:290-1.
2Langewar DN, Shroff HJ, Kohli MA, Hira SK. Cutaneous cryptococcosis and molluscum contagiosum occurring in the same lesion in a patient with AIDS. Indian J Dermatol Venereol Leprol 1998;64:25-8.