Indian Dermatology Online Journal

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 8  |  Issue : 2  |  Page : 94--99

Autologous serum and plasma skin tests in chronic spontaneous urticaria: A reappraisal


Muthu Sendhil Kumaran, Sonia Mangal, Tarun Narang, Davinder Parsad 
 Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Tarun Narang
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh
India

Aim: The objective of this study was to assess autologous serum skin test (ASST) vs autologous plasma skin test (APST) response in chronic spontaneous urticaria (CSU) patients and study the significance of intensity of positive responses in relation to clinicoepidemiological parameters. Materials and Methods: One hundred CSU patients and 100 age and sex-matched controls were recruited. The demographic and clinical features were recorded in all patients and routine investigations were performed. ASST and APST tests were performed as per the standard guidelines. Results: The mean duration of illness was 4.85 ± 5.07 years, 90% patients were APST (+), 68% ASST (+), and 22 patients were only APST (+). Positive predictive value (PPV) of ASST and APST was 90.7% and 95.7%, respectively. A significant inverse association was seen between thyroid status and serum IgE levels with APST and ASST positivity. Conclusion: APST appears to have better PPV and high intensity of positive response on autologous tests, and correlates with ANA positivity and angioedema.


How to cite this article:
Kumaran MS, Mangal S, Narang T, Parsad D. Autologous serum and plasma skin tests in chronic spontaneous urticaria: A reappraisal.Indian Dermatol Online J 2017;8:94-99


How to cite this URL:
Kumaran MS, Mangal S, Narang T, Parsad D. Autologous serum and plasma skin tests in chronic spontaneous urticaria: A reappraisal. Indian Dermatol Online J [serial online] 2017 [cited 2017 Sep 26 ];8:94-99
Available from: http://www.idoj.in/article.asp?issn=2229-5178;year=2017;volume=8;issue=2;spage=94;epage=99;aulast=Kumaran;type=0