Indian Dermatology Online Journal

CASE REPORT
Year
: 2017  |  Volume : 8  |  Issue : 3  |  Page : 192--194

Disseminated cutaneous trichosporonosis in an adult bone marrow transplant patient


A. M. Y. Yong1, SS Yang1, KB Tan2, SA Ho1 
1 Department of Dermatology, National University Health System, Singapore
2 Department of Pathology, National University Health System, Singapore

Correspondence Address:
A. M. Y. Yong
National University Health System, 5 Lower Kent Ridge Rd
Singapore

The Trichosporon species are yeast-like opportunistic pathogens in immunocompromised patients. Trichosporon asahii infections have been reported in pediatric bone marrow transplant (BMT) patients. However, its incidence is low in the adult literature. A 52-year-old Chinese woman who was diagnosed with acute myeloid leukemia received induction chemotherapy and underwent allogenic bone marrow transplant, which was complicated by a relapse and required salvage chemotherapy. She developed persistent non-neutropenic fever secondary to presumed hepatosplenic candidiasis. Antifungal therapy with fluconazole and anidulafungin was administered. She remained febrile and tender dusky nodules appeared over all the four limbs. Histopathological examination and fungal culture identified T. asahii. Oral voriconazole was initiated with complete resolution of her lesions. The Trichosporon species is a frequently isolated yeast species from cancer patients. Voriconazole has become the first choice agent against Trichosporon. We highlight the increased awareness and clinical suspicion required for diagnosis and subsequent management in similar adult patients.


How to cite this article:
Yong A, Yang S S, Tan K B, Ho S A. Disseminated cutaneous trichosporonosis in an adult bone marrow transplant patient.Indian Dermatol Online J 2017;8:192-194


How to cite this URL:
Yong A, Yang S S, Tan K B, Ho S A. Disseminated cutaneous trichosporonosis in an adult bone marrow transplant patient. Indian Dermatol Online J [serial online] 2017 [cited 2019 Nov 20 ];8:192-194
Available from: http://www.idoj.in/article.asp?issn=2229-5178;year=2017;volume=8;issue=3;spage=192;epage=194;aulast=Yong;type=0