Indian Dermatology Online Journal

REVIEW ARTICLE
Year
: 2019  |  Volume : 10  |  Issue : 3  |  Page : 234--243

What is new in narrow-band ultraviolet-B therapy for vitiligo?


Urmi Khanna1, Sujay Khandpur2 
1 Department of Dermatology, Cleveland Clinic, Cleveland, Ohio, USA
2 Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Sujay Khandpur
Department of Dermatology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
India

Vitiligo is an acquired disorder of skin pigmentation that produces significant psychological impact especially in those with skin of color. Narrow-band ultraviolet B (NB-UVB) therapy, which was first used in vitiligo in 1997 by Westerhof and Nieuweboer-Krobotova, has emerged as one of the safest and most effective therapy for this dermatosis. The light source used for NB-UVB phototherapy is the TL-01 lamp, and the most common model of the NB-UVB phototherapy device is the upright in-office booth or chamber which has 24–48 such lamps. In recent years, there have been several advances in the understanding of the mechanism of action of NB-UVB and the use of combination treatments, many of which increase the efficacy of NB-UVB. In 2017, the Vitiligo Working Group made vital recommendations on the dosage, frequency, and safety of NB-UVB in vitiligo. Furthermore, home phototherapy devices are gaining popularity as they lead to an improved patient compliance. There is still need for large multicenter randomized controlled trials to assess benefits of home phototherapy in vitiligo and studies investigating additional benefits of phototherapy following surgical therapy.


How to cite this article:
Khanna U, Khandpur S. What is new in narrow-band ultraviolet-B therapy for vitiligo?.Indian Dermatol Online J 2019;10:234-243


How to cite this URL:
Khanna U, Khandpur S. What is new in narrow-band ultraviolet-B therapy for vitiligo?. Indian Dermatol Online J [serial online] 2019 [cited 2019 Jun 25 ];10:234-243
Available from: http://www.idoj.in/article.asp?issn=2229-5178;year=2019;volume=10;issue=3;spage=234;epage=243;aulast=Khanna;type=0