• Users Online: 1302
  • Print this page
  • Email this page
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Citation statistics : Table of Contents
   2014| April-June  | Volume 5 | Issue 2  
    Online since April 21, 2014

 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Cited Viewed PDF
LETTERS TO THE EDITOR
Remote reverse Koebner phenomenon in generalized granuloma annulare
Kikkeri N Naveen, Varadraj V Pai, Sharatchandra B Athanikar, Gaurang Gupta, Hassan A Parshwanath
April-June 2014, 5(2):219-221
DOI:10.4103/2229-5178.131137  PMID:24860769
  4 4,484 243
ORIGINAL ARTICLES
Total serum immunoglobulin E in patients with alopecia areata
Ola Ahmed Bakry, Rania Mohamed Azmy El Shazly, Mohamed Ahmed Basha, Hanan Mostafa
April-June 2014, 5(2):122-127
DOI:10.4103/2229-5178.131076  PMID:24860742
Context: Alopecia areata (AA) is a common form of localized, non-scarring hair loss. The pathogenesis of the disease is unknown. Previous evidence suggested the involvement of Th2 cytokines in disease pathogenesis. Aim: To determine serum level of total IgE, this is mainly influenced by Th2 cytokines, in Egyptian patients with AA. Materials and Methods: Fifty subjects with AA (28 males and 22 females) were selected from Dermatology Outpatient Clinic, Menoufiya University Hospital from February 2012 to December 2012. Subjects with other conditions that might elevate serum IgE were excluded from the study. Fifty age- and sex-matched healthy subjects were selected as a control group. Venous blood samples were taken from cases and controls for measurement of total serum IgE by enzyme-linked immunosorbent assay. Skin biopsy was taken from every case from an active area of hair loss. Results: Total serum IgE was elevated in 27 (54%) cases. Its values among patients ranged from 13.5 IU/ml to 780 IU/ml. There was a statistically significant difference between cases and controls with regard to mean value of serum IgE (P < 0.05). Mean value of IgE did not vary significantly with disease severity, patients' age, patients' gender, disease duration, site of lesions, and positive family history of AA. No correlation was found between serum IgE levels and histopathological changes detected in examined cases. Conclusions: Total serum IgE is elevated in AA. This elevation is not related to age, gender, disease duration, disease severity, site of affection or family history of AA.
  4 2,699 439
CASE REPORTS
Non pigmenting mucosal fixed drug eruption due to tadalafil: A report of two cases
Sudip Das, Suchibrata Das, Joyeeta Chowdhury, Dulal Chandra Bhanja
April-June 2014, 5(2):167-169
DOI:10.4103/2229-5178.131091  PMID:24860753
Various 'sex-stimulant' medicines with fancy names and attractive packaging are available over the counter. Most contain phosphodiesterase 5 inhibitors in various strengths, often with herbal additions. These drugs are used erratically by the lay public, driven by folklore that such usage leads to increase in the length, girth or firmness of the penis. Such indiscriminate use by an otherwise healthy population leads to undue side effects.
  3 3,168 253
Pansclerotic morphea: A male child with hemiatrophy of lower limb
Malay K Dasgupta, Chaitali Patra, Shatanik Sarkar, Sabyasachi Das
April-June 2014, 5(2):170-172
DOI:10.4103/2229-5178.131092  PMID:24860754
Morphea is a variant of localized scleroderma in which lesions are usually limited to the skin and subcutaneous tissue. Pansclerotic morphea is a rare atrophying and sclerosing type of morphea. It can follow a comparatively benign course with spontaneous resolution of symptoms, or sometimes can lead to a variety of complications resulting in progressive disability. We report a case of Pansclerotic morphea in an 8-year-old male child involving one lower extremity with extension to the lower trunk. It was associated with deformity and hemiatrophy of that limb, leading to restriction of normal day-to-day activity. The case is being reported in view of its rare occurrence in conjunction with other rarer features.
  3 2,387 427
Sjögren-Larsson syndrome: A study of clinical symptoms in six children
Sahana M Srinivas, KN Vykunta Raju, Ravi Hiremagalore
April-June 2014, 5(2):185-188
DOI:10.4103/2229-5178.131099  PMID:24860759
Sjögren-Larsson syndrome (SLS) is a rare autosomal recessive disorder characterized by triad of congenital ichthyosis, spastic paresis, and mental retardation. It is an inborn error of lipid metabolism caused by deficiency of the enzyme fatty aldehyde dehydrogenase. We report our observations of six children with SLS.
  3 1,559 301
CASES FROM ACKERMAN ACADEMY
Medallion-like dermal dendrocytoma
Melissa Alexander, Lubna Rizwan, Adelle T Quintana, Viktoryia Kazlouskaya, Dirk Elston
April-June 2014, 5(2):198-200
DOI:10.4103/2229-5178.131110  PMID:24860763
Medallion-like dermal dendrocytoma is a benign cutaneous neoplasm that mimics dermatofibrosarcoma protuberans histologically. The distinction between these two entities is critical to prevent unnecessary wide excisions. Herein we describe an acquired MLDD in a 55-year-old female.
  3 964 190
DRUG PROFILE
Antioxidants in dermatology
Varadraj V Pai, Pankaj Shukla, Naveen Narayanshetty Kikkeri
April-June 2014, 5(2):210-214
DOI:10.4103/2229-5178.131127  PMID:24860765
Antioxidants neutralize free radicals produced by various environmental insults such as ultraviolet radiation, cigarette smoke and air pollutants, thereby preventing cellular damage. The role of oxidative stress and antioxidants is known in diseases like obesity, atherosclerosis, and Alzheimer's disease. Herein we discuss the effects of oxidative stress on the skin and role of antioxidants in dermatology.
  3 5,224 1,393
CASE REPORTS
Hyperpigmentation in photo exposed patches of vitiligo following tacrolimus therapy
Kanika Sahni, Vishal Gupta, Neena Khanna
April-June 2014, 5(2):164-166
DOI:10.4103/2229-5178.131090  PMID:24860752
Vitiligo is an acquired pigmentary disorder, clinically characterized by depigmented macules caused by destruction of melanocytes in the affected skin. Half of all patients develop the disease in childhood and adolescence before the age of 20 years, making vitiligo an important skin disease of childhood. There are numerous studies in the literature that suggest the efficacy of topical tacrolimus in vitiligo, without serious adverse effects. We describe a case of vitiligo in a pediatric patient who developed hyperpigmentation in the periorbital lesions of vitiligo with the use of topical tacrolimus. To the best of our knowledge, this is only the second such reported occurrence in a patient with vitiligo.
  2 9,086 424
Juvenile pemphigoid nodularis: Report of a rare case
Dipti Das, Debabrata Bandyopadhyay
April-June 2014, 5(2):189-192
DOI:10.4103/2229-5178.131101  PMID:24860760
Bullous pemphigoid is an autoimmune blistering disease that is rare in childhood. Pemphigoid nodularis is a variant of BP that is exceedingly rare in children. Pemphigoid nodularis is characterized by overlapping clinical features of both prurigo nodularis and BP. We report here a case of pemphigoid nodularis in an 11-year-old boy.
  2 2,347 599
Aggressive Angiomyxoma
L Padmavathy, L Lakshmana Rao, M Dhana Lakshmi, N Sylvester
April-June 2014, 5(2):151-153
DOI:10.4103/2229-5178.131085  PMID:24860748
Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid) matrix. [1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence. [2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its rarity.
  2 2,339 228
Segmental lichen planus pigmentosus: An unusual presentation
Y Hari Kishan Kumar, Anagha Ramesh Babu
April-June 2014, 5(2):157-159
DOI:10.4103/2229-5178.131087  PMID:24860750
Lichen planus pigmentosus (LPP) is a distinct clinical entity commonly encountered in the Indian population. It is considered a variant of lichen planus (LP). A 40-year-old male presented with asymptomatic hyperpigmented macules in a segmental distribution since 10 years that were clinically and histopathologically suggestive of LPP. We propose the terminology "segmental lichen planus pigmentosus" and report this unusual presentation.
  2 11,285 674
LETTERS TO THE EDITOR
Idiopathic cutaneous pseudolymphoma: An enigma
Vinod Prabhu, Aslam Shivani, Vishrabdha R Pawar
April-June 2014, 5(2):224-226
DOI:10.4103/2229-5178.131143  PMID:24860772
  2 1,942 338
THROUGH THE LENS
Elastosis perforans serpiginosa
Ludimila Noleto de Rezende, Mónica Gauto Nuñez, Thaís Genn Clavery, Eneida Genn Constancio, Mayra Carrijo Rochael, Gabriela Juncá T Pires, Omar Lupi
April-June 2014, 5(2):236-237
DOI:10.4103/2229-5178.131156  PMID:24860779
  2 952 214
CASE REPORTS
Proteus syndrome: A rare cause of gigantic limb
Nandini Chakrabarti, Chandan Chattopadhyay, Majhi Bhuban, Salil Kumar Pal
April-June 2014, 5(2):193-195
DOI:10.4103/2229-5178.131108  PMID:24860761
A congenital disorder with variable manifestations, including partial gigantism of the hands and feet with hypertrophy of soles, nevi, hemihypertrophy, gynecomastia, macrocephaly and other skull abnormalities, and abdominal lipomatosis. The cause is unknown, although a genetic origin, generally of autosomal-dominant transmission, has been conjectured. Symptoms can be treated, but there is no known cure. We present the case of a young male with grotesque overgrowth of the right lower limb, splenomegaly and multiple nevi. Angiography revealed venous malformation within the limb. The findings are in conformity to the criteria for the Proteus syndrome.
  1 1,529 225
Livedo reticularis in type 2 lepra reaction: A rare presentation
Kikkeri Narayanasetty Naveen, Sharatchandra Bhimrao Athanikar, Spandana Prakash Hegde, Vidisha Sharatchandra Athanikar
April-June 2014, 5(2):182-184
DOI:10.4103/2229-5178.131097  PMID:24860758
Type 2 lepra reaction or erythema nodosum leprosum (ENL) is an immune complex syndrome that occurs mostly in lepromatous leprosy and sometimes in borderline lepromatous leprosy patients. We present an untreated case of lepromatous leprosy, who presented with type 2 lepra reaction and livedo reticularis. Livedo reticularis, though seen in lucio phenomenon, is not a part of type 2 lepra reaction. The case is being reported for its rarity.
  1 1,618 249
Could cryosurgery be an alternative treatment for basal cell carcinoma of the vulva?
Verónica Garza-Rodríguez, Alberto De la Fuente García, Myrna Alejandra Cardoza Torres, Minerva Gómez Flores, Gildardo Jaramillo Moreno, Jorge Ocampo Candiani
April-June 2014, 5(2):160-163
DOI:10.4103/2229-5178.131089  PMID:24860751
Basal cell carcinomas (BCC) on the genital area account for less than 1% of all BCCs. Surgical management is indicated. Recurrence rate of vulvar BCC has been reported to be 10-20%. Mohs micrographic surgery (MMS) is a superior surgical option. Other treatments include radiation and topical immuntherapy. Cryosurgery for vulvar BCC has not been reported. We present the case of a 88-year-old Hispanic woman with a vulvar ulcer that was confirmed as BCC by histopathology and treated with liquid nitrogen cryosurgery. Control biopsy was performed on day 90 was negative for BCC. No clinical evidence of recurrence was detected after one year. Although, the vulva is considered to be a high-risk site with respect to BCC and MMS is the gold standard for treatment, the delicate nature of the area may preclude complete removal by a surgical technique without compromising vital anatomical function. Liquid nitrogen cryosurgery uses the effects of extreme cold to effect deep destruction of the tumor and surrounding tissues. This is the first report of a vulvar BCC successfully treated with liquid nitrogen cryosurgery. We suggest this technique could be of benefit as an alternative treatment in cases where excisional procedures cannot be performed.
  1 1,056 75
A rare presentation of Klippel-Trenaunay syndrome
Tanweer Karim, Upvan Singh, Navdeep S Nanda
April-June 2014, 5(2):154-156
DOI:10.4103/2229-5178.131086  PMID:24860749
The Klippel-Trenaunay syndrome (KTS) is a congenital disorder characterized by capillary malformation, varicosities and bony and soft tissue hypertrophy. This disease has several morbidities like bleeding, deep venous thrombosis, embolic complications and in some cases enlargement of limb that may require amputation. Vascular malformations are segmented and never cross midline. However, we came across a case, a 45-year-old male, who presented with varicosity of veins and deformity of left lower limb besides cavernous hemangiomas (port-wine stains) scattered all over his face, chest, back, gluteal region, groin and legs since birth. Multiple paravertebral soft tissue masses and bladder hypertrophy were also noted due to involving neurofibromatosis. Simultaneous occurrence of KTS and neurofibromatosis is rarely seen in clinical practice.
  1 2,509 388
Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
Tirthankar Gayen, Anupam Das, Sudipta Roy, Shamick Biswas, Kaushik Shome, Satyendra N Chowdhury
April-June 2014, 5(2):176-178
DOI:10.4103/2229-5178.131094  PMID:24860756
Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.
  1 1,443 212
Pseudoepitheliomatous keratotic and micaceous balanitis of Civatte
Sudip Das, Loknath Ghoshal
April-June 2014, 5(2):148-150
DOI:10.4103/2229-5178.131084  PMID:24860747
Pseudoepitheliomatous, keratotic, and micaceous balanitis is a rare condition characterized by verrucous excrescences with scaling. Most patients are over the age of 50 and frequently have been circumcised for phimosis in adult life. We present here a case of 35-year-old male patient with long standing phimosis presenting with a firm whitish plaque on the glans penis. The crusts were micaceous in nature. Histopathologically, there was pseudoepitheliomatous hyperplasia with acanthosis and no cellular atypia. The condition was explained to the patient and treatment options discussed. The patient was started on topical 5-fluorouracil cream on a daily basis as he did not express consent for operative intervention.
  1 4,148 339
LETTERS TO THE EDITOR
A study of the prevalence and precipitating factors of pruritus in pityriasis versicolor
Ankita Kaushik, Hyacinth P Pinto, Ramesh M Bhat, D Sukumar, MK Srinath
April-June 2014, 5(2):223-224
DOI:10.4103/2229-5178.131141  PMID:24860771
  1 1,304 289
ORIGINAL ARTICLES
Role of the ACTH test and estimation of a safe dose for high potency steroids in vitiligo: A prospective randomized study
Alberto de la Fuente-García, Minerva Gómez-Flores, Leonardo Mancillas-Adame, Jorge Ocampo-Candiani, Oliverio Welsh-Lozano, Jesús Zacarías Villarreal Pérez, José Gerardo González-González, Fernando Lavalle-González
April-June 2014, 5(2):117-121
DOI:10.4103/2229-5178.131071  PMID:24860741
Background: Topical corticosteroids are used as first line of therapy for vitiligo, although side effects such as adrenal insufficiency are possible. Objectives: To establish the role of ACTH test before, during, and after treatment with high potency topical steroids; to determine if adrenal insufficiency occurs secondary to the use of high potency topical steroids in patients with vitiligo and intact cutaneous barrier; and also to determine response to treatment and side effects. Materials and Methods: Forty-four adults with non-segmental vitiligo affecting 20% or less of the body surface area were included and randomized to receive topical clobetasol propionate 0.05% cream (group 1) or placebo (group 2) for 12 weeks, with a maximum dose of 50 g per week. The placebo group was crossed over after week 6 and started on clobetasol until completion of the study. Serum cortisol levels with the 1 μg ACTH test were determined at baseline and on weeks 6 and 12. Results: No adrenal insufficiency was detected nor statistical significance was achieved when comparing cortisol levels between and within the groups at baseline and weeks 6 and 12. Group 1 had a better response to therapy but with more side effects. Conclusions: Doses of 50 g or less per week of clobetasol during a period of 12 weeks are safe on adult vitiligo patients, although local side effects are possible. Repigmentation rates were incomplete with single steroid therapy, making combined therapy a better option.
  1 1,915 366
Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris
Sanjiv V Choudhary, Taru Aghi, Shazia Bisati
April-June 2014, 5(2):128-131
DOI:10.4103/2229-5178.131079  PMID:24860743
Aims: To study and compare the efficacy and safety of topical terbinafine hydrochloride 1% cream and eberconazole nitrate 1% cream in localized tinea corporis and cruris. Methods and Materials: Patients were randomized after considering various inclusion and exclusion criteria into two groups. Group A (treated with terbinafine 1% cream for 3 weeks) and group B (treated with eberconazole 1% cream for 3 weeks). The sample size was of 30 patients with 15 patients in each group. Assessment of clinical improvement, KOH mount and culture was done weekly up to 3 weeks to assess complete cure. Results: On comparison between the two groups, it was observed that eberconazole nitrate 1% cream was as effective as terbinafine hydrochloride 1% cream at the end of first (Non-sisgnificant (NS); P = 0.608, 1.00), second (NS; P = 0.291,0.55), and third (P = 1.00, 1.00) weeks with statistically nonsignificant clinical and mycological values. In both the groups, clinically no significant local side effects were noticed. Conclusions: The newer fungistatic eberconazole nitrate 1% cream was as effective as the fungicidal terbinafine hydrochloride 1% cream. Both the drugs showed good tolerability with no adverse effects.
  1 12,406 798
Metabolic syndrome in patients with psoriasis: A comparative study
Sristi Lakshmi, Amiya Kumar Nath, Carounanidy Udayashankar
April-June 2014, 5(2):132-137
DOI:10.4103/2229-5178.131080  PMID:24860744
Background: Psoriasis patients are at increased risk of developing the metabolic syndrome (MS). Proinflammatory cytokines such as tumor necrosis factor-α, interleukin-6 that are increased in the psoriatic plaques are known to contribute to features of MS such as hypertension, dyslipidemia and insulin resistance. Aims: (1) To establish the frequency of MS in patients with psoriasis. (2) To study the risk factors associated with MS in psoriasis. Materials and Methods: A hospital based comparative study was conducted involving 40 adult patients with psoriasis and 40 age- and sex-matched controls. All participants were evaluated for components of MS. Results: Both groups included 31 males and 9 females. The mean age of the cases and controls were 49.95 years and 49.35 years, respectively. Psoriasis patients with MS had a statistically significant higher mean age (56.31 ± 11.36 years) compared with those without MS (46.89 ± 11.51 years). MS was present in 13 out of 40 (32.5%) patients with psoriasis and 12 out of 40 (30%) controls; this difference was not statistically significant. Higher age and female gender correlated with the presence of MS in psoriasis patients. The presence of MS in psoriasis patients was statistically independent of psoriasis area severity index score, body surface area involvement or psoriatic arthropathy. Conclusion: Our results suggest that there is no close correlation between psoriasis and MS in South Indian patients.
  1 3,544 754
Clinical profile of cutaneous manifestations with and without hematologic disease: A comparative study
Sushil Yashwant Pande, Vidya Kharkar
April-June 2014, 5(2):138-143
DOI:10.4103/2229-5178.131081  PMID:24860745
Aim: The aim was to study the clinical profile of cutaneous manifestations of hematologic disorders and to compare it with that of non-hematologic disorders. Materials and Methods: Cutaneous manifestations of hematologic diseases fall in seven well-defined categories. A total of 153 outpatients with skin manifestations fitting in these categories were enrolled in a comparative study of 1-year duration. Clinical profile of these cutaneous manifestations was studied and any underlying hematologic disorder was ruled out with the help of a hematologist. Difference in the clinical profile of cutaneous manifestations with and without hematologic diseases was studied. Result: Of the 26,174 outpatients during the study period, 153 had cutaneous manifestations fitting in the categories of hematologic disorders. Of these 153 patients, 33 had hematologic disease as the cause of their cutaneous manifestation (21.57%), whereas 78.42% had no hematologic disorder. Disorders of hemostasis formed the largest group (36%) followed by cutaneous deposits/infiltrations (15%), vesiculobullous disorders (6%), and cutaneous vasculitis (9%) were least commonly associated with hematologic disorders. Conclusion: Hematologic diseases are associated with complex array of cutaneous manifestations. The incidence of hematologic disease-associated cutaneous manifestations was 0.13%. Findings of this study will help dermatologists and physicians with the early recognition of cutaneous signs of hematologic disorders.
  1 1,565 307
THROUGH THE LENS
Suction purpura
Lalit Kumar Gupta, Ashok K Khare, Sonakshi Pargi, Asit Mittal
April-June 2014, 5(2):231-231
DOI:10.4103/2229-5178.131149  PMID:24860776
  1 963 189
CASE REPORTS
Nevirapine induced toxic epidermal necrolysis and non-Hodgkin lymphoma in a Human Immunodeficiency Virus positive patient
Leelavathy Budamakuntla, Eswari Loganathan, Shwetha Suryanarayan, Kumar Abhishek, Sacchidanand Sarvajnamurthy
April-June 2014, 5(2):179-181
DOI:10.4103/2229-5178.131096  PMID:24860757
Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) is one of the important components of highly active antiretroviral therapy. It is sometimes associated with life-threatening adverse reactions. Here we report one such patient who developed toxic epidermal necrolysis (TEN), leucopenia and hepatotoxicity secondary to intake of nevirapine. This patient was also diagnosed to have non-Hodgkin lymphoma grade IV of anal canal for which he was given radiotherapy and two cycles of chemotherapy. The treating physicians should carefully monitor patients on NNRTI-based antiretroviral therapy so that fatalities due to adverse drug reactions can be prevented with timely intervention.
  - 1,293 218
Rud's syndrome
K Pavani, B. S. N. Reddy, B Amar Singh
April-June 2014, 5(2):173-175
DOI:10.4103/2229-5178.131093  PMID:24860755
Rud's syndrome is a rare autosomal recessive hereditary disorder characterized by congenital ichthyosis, epilepsy, dwarfism, sexual infantilism, polyneuritis, and macrocytic anemia. We report here an interesting case of this disorder in an 18-year-old girl for its rarity and academic interest.
  - 3,518 307
Hypomelanosis of Ito with an unusual pulmonary abnormality in an infant
Ramesh Y Bhat, Saikat Patra, P. V. Chaitanya Varma, K Prakashini
April-June 2014, 5(2):196-197
DOI:10.4103/2229-5178.131109  PMID:24860762
Hypomelanosis of Ito (HI) is a neurocutaneous syndrome characterized by hypopigmented cutaneous lesions and extracutaneous manifestations frequently affecting the nervous system and the musculoskeletal system. Dysmorphic features, dental, ophthalmic, gastrointestinal, cardiac, and renal abnormalities are described in a minority of patients. The authors describe a 4-month-old infant having HI with unusual pulmonary hypoplasia that has not been reported so far.
  - 1,261 179
COMMENTARY
Cerebriform intradermal nevus: A rare entity and its associations
Meghana Phiske
April-June 2014, 5(2):115-116
PMID:24860740
  - 1,714 257
EDITORIAL
The benefit of a case report
Terence J Ryan
April-June 2014, 5(2):113-114
DOI:10.4103/2229-5178.131062  PMID:24860739
  - 1,140 253
LETTERS TO THE EDITOR
Art of publication: The title, abstract, and cover letter
Kieran Walsh
April-June 2014, 5(2):226-226
DOI:10.4103/2229-5178.131144  PMID:24860773
  - 711 235
Pagetoid dyskeratosis of the forehead
Pankaj Salphale, Meera Thomas
April-June 2014, 5(2):215-216
DOI:10.4103/2229-5178.131128  PMID:24860766
  - 785 164
Pemphigus vulgaris: A dermatological sequel of severe H1N1 infection
Preema Sinha, Manas Chatterjee, Biju Vasudevan
April-June 2014, 5(2):216-217
DOI:10.4103/2229-5178.131131  PMID:24860767
  - 876 185
Verrucous carcinoma of the finger: A rare site of occurrence
Girish P Narayana, I Sandhya
April-June 2014, 5(2):218-219
DOI:10.4103/2229-5178.131133  PMID:24860768
  - 865 167
Acrocyanosis with intrahepatic carcinoid tumor
K.V.S. Hari Kumar, Amit Kumar, Deepak Tomar, AK Gupta
April-June 2014, 5(2):221-223
DOI:10.4103/2229-5178.131139  PMID:24860770
  - 787 137
MUSINGS, OPINIONS, TIPS AND EXPERIENCES
Human pigmentation: A side effect adapted from a primitive organism's survival, acting through cell attachment with an affinity for the keratinocyte and for elastin: Part I
Sanju Arianayagam, Terence J Ryan
April-June 2014, 5(2):201-209
DOI:10.4103/2229-5178.131125  PMID:24860764
Pigmentation featured millions of years ago and perhaps began with an amoeba frightening off a predator with some agent such as dopamine to prevent its attachment for phagocytosis by an enemy. This paper suggests that the environmental forces of grip and stick deserve greater emphasis and that mechanical forces involved in grip and stick or release from attachment, all point to control of proteases underlying pigmentation. There is an affinity for elastin as a pathway for melanin to exit its peripheral location in the epidermis into lymphatics and play a humeral role in defense mechanisms. The hair follicle follows the epidermal-dermal pattern of behavior with an affinity for elastin, a controlling function of melanin and through the bulge, an influence of mechanical forces and control by protease inhibitors.
  - 3,147 332
ORIGINAL ARTICLES
A burst in the incidence of viral exanthems
Carmen Maria Salavastru, Anca Mihaela Stanciu, Klaus Fritz, George Sorin Tiplica
April-June 2014, 5(2):144-147
DOI:10.4103/2229-5178.131083  PMID:24860746
Background: Vaccines have a major role in eradication programs of viral diseases. Vaccines against measles, rubella, and varicella are included in the vaccination schedules for children in most countries. Objective: A comparative analysis between 2011 and 2012 was performed to investigate if the number of patients with viral exanthemas reported to our clinic in 2012 was increased. Materials and Methods: Patients were grouped in four categories: rubella, measles, varicella and other viral exanthemas. Results: Between January and April 2011, there were registered 37 cases with viral exanthemas: 69.5% presented with varicella and 30.5% with other viral exanthemas. Between January and April 2012, there were 178 cases registered with viral eruption, of which 37% were of other viral exanthemas, 35.4% rubella, 19.7% measles and 7.9% varicella. The highest incidence was seen in patients aged between 20 and 29 years (52.2%), with 21% having measles, 32.2% rubella, 9% varicella and 37.6% having other exanthemas. In 2012, the number of cases of viral exanthemas increased 5 times, with important outbreaks of new cases of measles and rubella. Conclusions: Although vaccines against measles and rubella were being used since 1979 and 1998 respectively, it was only in 2004, that these vaccines became part of the mandatory vaccination schedule. Although persons under 32 years should be protected against measles infection if they are previously vaccinated, more than 90% of the registered cases of measles occurred in such patients. The patients registered between January and April 2011 were mostly pediatric. Adults also were much more affected with measles, rubella, or varicella viruses in 2012 than in 2011.
  - 4,006 352
SKINDIA QUIZ
SkIndia Quiz 13: Scars on the skin, scars in the heart
Nitin Nadkarni, Sharmila Patil, Kiran Godse, Manjyot Gautam, Prachi Bhattar
April-June 2014, 5(2):227-228
DOI:10.4103/2229-5178.126141  
  - 2,096 219
THROUGH THE LENS
Chronic, fluctuating, grouped, erythematous papules around the mouth
Sankha Koley, Rajesh Kumar Mandal
April-June 2014, 5(2):229-230
DOI:10.4103/2229-5178.131147  PMID:24860775
  - 1,363 184
Palmoplantar keratoderma with dental abnormalities
Feroze Kaliyadan, Ajit Nambiar
April-June 2014, 5(2):232-234
DOI:10.4103/2229-5178.131152  PMID:24860777
  - 1,614 184
A classical case of punctate palmoplantarkeratoderma: A rare entity
Kikkeri Narayanasetty Naveen, Varadraj V Pai
April-June 2014, 5(2):235-235
DOI:10.4103/2229-5178.131153  PMID:24860778
  - 930 164
  Feedback 
  Subscribe 
  Search 
  Advanced Search 
  Apply as Reviewer