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CASE REPORT
Year : 2010  |  Volume : 1  |  Issue : 1  |  Page : 18-20

Darier-White disease in siblings responding to isotretinoin


Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Kankanady, Mangalore - 575 002, India

Correspondence Address:
Ramesh M Bhat
Department of Dermatology, Father Muller Medical College Hospital, Kankanady, Mangalore - 575 002
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.73252

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Darier-White disease (keratosis follicularis) is a rare disorder of keratinization involving the epidermis, mucous membranes, and nails. It is said to occur as a result of mutation in the ATP2A2 gene located on chromosome 12q23-24.1. In this article we present the case of two brothers with exacerbations of Darier-White disease who responded very well to systemic retinoids without any side effects within 2 weeks of commencing treatment.


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