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Year : 2013  |  Volume : 4  |  Issue : 2  |  Page : 160-161  

SkIndia Quiz 9: Solitary cystic nodule with a horn on the thigh of elderly male

Department of Dermatology, Dr. L. H. Hiranandani Hospital, Powai, Mumbai, India

Date of Web Publication17-Apr-2013

Correspondence Address:
Rameshwar M Gutte
Department of Dermatology, OPD No. 128, 1st Floor, Dr. L. H. Hiranandani Hospital, Powai, Mumbai - 400 076
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5178.105497

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How to cite this article:
Gutte RM. SkIndia Quiz 9: Solitary cystic nodule with a horn on the thigh of elderly male. Indian Dermatol Online J 2013;4:160-1

How to cite this URL:
Gutte RM. SkIndia Quiz 9: Solitary cystic nodule with a horn on the thigh of elderly male. Indian Dermatol Online J [serial online] 2013 [cited 2021 Aug 1];4:160-1. Available from: https://www.idoj.in/text.asp?2013/4/2/160/105497

A 50-year-old male presented with an asymptomatic swelling on left thigh. Swelling increased slowly to the present size over a period of 4 years. Also he noticed development of a verrucous growth on swelling since last 1 year [Figure 1]. There was no any other complaint. His cutaneous and systemic examination revealed no any other abnormality. A wide surgical excision was done and specimen was sent for histopathology. Histopathologic findings are shown in [Figure 2], [Figure 3], [Figure 4], [Figure 5].
Figure 1: Solitary skin-colored nodule over the thigh with an overlying cutaneous horn

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Figure 2: Upper part of dermal cyst showing epidermoid keratinization with granular layer (H and E, ×40)

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Figure 3: Sharp transition from epidermoid to pilomatrical keratinization in the cyst wall (H and E, ×100)

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Figure 4: lower part of cyst showing pilomatrical differentiation (short arrow) with basaloid island and area of transition in cyst wall (long arrow) (H and E, ×40)

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Figure 5: A basaloid island with calcification (H and E, ×100)

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   What is the diagnosis? Top

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   References Top

1.Takeda H, Miura A, Katagata Y, Mitsuhashi Y, Kondo S. Hybrid cyst: Case reports and review of 15 cases in Japan. J Eur Acad Dermatol Venereol 2003;17:83-6.  Back to cited text no. 1
2.Brownstein MH. Hybrid cyst: A combined epidermoid and trichilemmal cyst. J Am Acad Dermatol 1983;9:872-5.  Back to cited text no. 2
3.Kim MS, Lee JH, Son SJ. Hybrid cysts: A clinicopathological study of seven cases. Australas J Dermatol 2012;53:49-51.  Back to cited text no. 3
4.Requena L, Sánchez Yus E. Follicular hybrid cysts. An expanded spectrum. Am J Dermatopathol 1991;13:228-33.  Back to cited text no. 4
5.Kirkham N. Tumors and cysts of the epidermis. In: Elder DE, Elenitsas R, Johnson BL, et al. editors. Lever's Histopathology of the Skin. 10 th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2009. p. 791-849.  Back to cited text no. 5
6.Cooper PH, Fechner RE. Pilomatricoma-like changes in the epidermal cysts of Gardner's syndrome. J Am Acad Dermatol 1983;8:639-44.  Back to cited text no. 6
7.Stevens CS. Follicular cysts: How should we name them? J Am Acad Dermatol 1985;12:367-8.  Back to cited text no. 7
8.de la Torre JP, Saiz A, García-Arpa M, Rodríguez-Peralto JL. Pilomatricomal horn: A new superficial variant of pilomatricoma. Am J Dermatopathol 2006;28:426-8.  Back to cited text no. 8


  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5]


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