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Year : 2014  |  Volume : 5  |  Issue : 2  |  Page : 176-178

Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?

1 Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India
2 Department of Radiodiagnosis, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India

Correspondence Address:
Anupam Das
"Prerana", 19, Phoolbagan, Kolkata - 700 086, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5178.131094

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Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.

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