| CASE REPORT |
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| Year : 2014 | Volume
: 5
| Issue : 5 | Page : 36-39 |
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Nodular colloid degeneration of the skin: Report of three cases with review and update
Alireza Ghanadan1, Kambiz Kamyab-Hesari1, Maryam Daneshpajouh2, Kamran Balighi2, Pedram Normohammadpour2
1 Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
Correspondence Address:
Dr. Alireza Ghanadan
Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran
Iran
 Source of Support: All Funding sources are provided by Tehran University of Medical Sciences,, Conflict of Interest: None  | Check |
DOI: 10.4103/2229-5178.144527
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Nodular colloid degeneration (NCD) is a rare dermatological disorder and uncommon type of colloid milium. The degeneration may be related to sun exposure. In this report, three cases, all presenting as multiple plaques and nodules over the nose and the face are depicted. Histologically, these nodular masses were homogeneous, with eosinophilic-cleaved materials expanding the papillary dermis and extending into the deep dermis. Periodic acid Schiff (PAS), crystal violet, and methyl-violet stains highlight the colloid material. All the three cases were finally diagnosed as NCD. NCD could be considered in any case with facial nodules and a long history of sun exposure. We suggest the long-term sun exposure as an etiologic factor; thus sun protection would be the most preventive and available treatment. |
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