|THROUGH THE LENS
|Year : 2015 | Volume
| Issue : 4 | Page : 304-305
Vaishali Wankhade1, Rajesh Singh1, Venus Sadhwani1, Purnima Kodate2
1 Department of Dermatology, Government Medical College and Hospital, Nagpur, Maharashtra, India
2 Department of Pathology, Government Medical College and Hospital, Nagpur, Maharashtra, India
|Date of Web Publication||8-Jul-2015|
Department of Dermatology, Government Medical College and Hospital, Nagpur, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Wankhade V, Singh R, Sadhwani V, Kodate P. Eccrine poroma
. Indian Dermatol Online J 2015;6:304-5
A 52-year-old male patient presented with asymptomatic nodule on the right palm since 2 years. It gradually increased in size and was not associated with pain, pruritus or bleeding in the lesion. Cutaneous examination revealed well-circumscribed, non-tender, sessile reddish nodule on the hypothenar eminence of right palm [Figure 1]. The nodule was completely excised and histopathological finding showed broad anastomosing bands of epithelial cells extending deep into the dermis [Figure 2]. The tumor cells were small uniform cuboidal with round nuclei and moderate amount of cytoplasm [Figure 3]. Based on the clinical and histological findings diagnosis of eccrine poroma was made.
|Figure 2: H and E (×10) epidermis with hyperkeratosis and broad anastomosing bands of epithelial cells extending deep into dermis|
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|Figure 3: H and E (×40) uniform small cuboidal cells with round nuclei and moderate amount of cytoplasm|
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| Discussion|| |
Eccrine poroma was first reported by Pinkus in 1956 and represents 10% of all sweat gland tumors.  It is a benign neoplasm originating from the intraepidermal ductal portion of the eccrine sweat duct. They are solitary, moist, exophytic bright red to flesh colored, painful, sessile or pedunculated papule or nodule usually occurring on palms or soles. A distinct feature is a cup shaped shallow depression from which the tumor protrudes.  Other sites of occurrence of poroma described in literature are chest, eye and buttocks. Occasionally, poroma may be pigmented and resembles basal cell carcinoma clinically and dermatoscopically.  Eccrine poromatosis is a rare clinical variant when there is development of multiple poromas occurring in patients on radiotherapy or polychemotherapy.  Eccrine porocarcinoma the malignant variant is more common in elderly patients with more than 50% of cases occurring in the lower limb.  Porocarcinoma evolving from a poroma is characterized by rapid growth up to 10 cm, bleeding and ulceration.  Histopathologically eccrine poroma arises within the lower portion of the epidermis and it extends downward into the dermis as tumor masses that often consists of broad anastomosing bands of epithelial cells. The cells are smaller than epidermal keratinocytes, have a uniform cuboidal appearance and a round deeply basophilic nucleus.  Intraepidermal type lesions are referred to as hidroacanthoma simplex. Poromas comprises lesions that span the epidermis, whereas dermal duct tumor exist entirely in dermis.
| References|| |
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[Figure 1], [Figure 2], [Figure 3]