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CASES FROM ACKERMAN ACADEMY
Year : 2015  |  Volume : 6  |  Issue : 6  |  Page : 422-424

Multiple nodules on the sole of the foot


1 NYIT-College of Osteopathic Medicine, New York, USA
2 Ackerman Academy of Dermatopathology, New York, USA
3 Polley Clinic, Wilson, North Carolina, USA

Correspondence Address:
Dirk M Elston
Ackerman Academy of Dermatopathology, 145 E, 32nd Street, 10th Floor, New York
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5178.169720

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Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations.


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