• Users Online: 1417
  • Print this page
  • Email this page

  Table of Contents  
Year : 2016  |  Volume : 7  |  Issue : 2  |  Page : 125-126  

Juvenile capillary hemangioma

1 Department of Pathology and Laboratory Medicine, Medanta-The Medicity, Gurgaon, Haryana, India
2 Department of Paediatrics, All India Institute of Medical Sciences, Bhubaneshwar, Odisha, India
3 Department of Nuclear Medicine, All India Institute of Medical Science, New Delhi, India

Date of Web Publication4-Mar-2016

Correspondence Address:
Dr. Smeeta Gajendra
Department of Pathology and Laboratory Medicine, Medanta-The Medicity, Sector - 38, Gurgaon - 122 001, Haryana
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5178.178079

Rights and Permissions

How to cite this article:
Gajendra S, Das RR, Sahoo MK. Juvenile capillary hemangioma. Indian Dermatol Online J 2016;7:125-6

How to cite this URL:
Gajendra S, Das RR, Sahoo MK. Juvenile capillary hemangioma. Indian Dermatol Online J [serial online] 2016 [cited 2021 Jan 19];7:125-6. Available from: https://www.idoj.in/text.asp?2016/7/2/125/178079


Hemangiomas are benign proliferative lesions of vascular origin, which are commonly present at birth and may become more apparent at any age of life. Juvenile hemangioma may be located on any part of the body surface but is most common in the head and neck region in young children, with a girl to boy ratio of 1:3.[1],[2] It may present in skin, subcutaneous tissue, mucous membranes of lips, mouth, or internal viscera. Intramuscular hemangiomas are rare, accounting for 0.8% of all benign vascular tumors. They occur most often in young children and usually involve the lower extremities, especially the thigh. Some grow rapidly to involve the whole limb.[1],[3] Herein we describe a 2-month-old female child presenting with right limb swelling since birth. She presented with sudden increase in leg swelling with erythema [Figure 1] and fever since two weeks. The baby was of full-term gestation and delivery was normal. On examination, the swelling was warm and indurated with mild tenderness. Hematological parameters were within normal limits. A radiograph revealed a diffuse soft tissue shadow without any bony involvement or periosteal reaction. The differential diagnoses considered were subacute osteomyelitis, eosinophilic granuloma, fibrosarcoma, Ewing's sarcoma, and other rare tumors. The child underwent a diagnostic tru-cut biopsy. Histopathology revealed intramuscular lobulated cellular growth with intervening fibrillar connective tissue. These lobules contained plump proliferating endothelial cells, a combination of numerous well and poorly canalized blood vessels, which are lined by endothelial cells [Figure 2]. A final diagnosis of benign juvenile intramuscular capillary hemangioma was made. The child returned after six months with partial regression of the swelling. A complete regression was observed at one year.
Figure 1: Right whole leg swelling with erythema

Click here to view
Figure 2: Histopathology showing proliferating of endothelial cells in lobules with intervening stroma (a, Hematoxylin and Eosin, 20×), (b, Reticulin stain, 20û)

Click here to view

Juvenile hemangiomas are benign vascular tumors, characterized by a rapid proliferative phase (0-1 years) followed by spontaneous involution (1-5 years) with continued improvement for up to 12 years (involuted phase).[4] It may present with a sudden enormous increase in the swelling posing suspicion of a rapidly progressing malignant tumor. Surgical treatment is required in approximately 60% of all hemangiomas. Superficial lesions are usually amenable to surgical excision. A wide excision during proliferative phase does not always lead to complete cure, and should be avoided due to risk of major blood loss and nerve injury. Recurrence rates following surgery can be as high as 18%.[5] In our case, the hemangioma underwent a rapid involution phase. Hence, careful observation could be recommended for spontaneous regression in juvenile capillary hemangioma, wherein the lesion does not pose any life-threatening complications or impair function.

Financial support and sponsorship

No honorarium, grant, or other form of payment was given to anyone to produce the manuscript.

Conflicts of interest

There are no conflicts of interest.

   References Top

Devalia KL, Mehta R, Yagnik MG. Benign juvenile hemangioma - A case report. Acta Orthop 2006;77:171-3.  Back to cited text no. 1
Bhagalia SR, Pardhe N, Gupta M, Jain M. Juvenile hemangioma: A case report with an emphasis on its clinical phases (evolution and involution), and immunohistochemically distinctive physiologic differences. J Oral Maxillofac Pathol 2011;15:316-9.  Back to cited text no. 2
[PUBMED]  Medknow Journal  
Cohen AJ, Youkey JR, Clagett GP, Huggins M, Nadalo L, d'Avis JC. Intramuscular hemangioma. JAMA 1983;249:2680-2.  Back to cited text no. 3
Hasan Q, Tan ST, Gush J, Davis PF. Altered mitochondrial cytochrome b gene expression during the regression of hemangioma. Plast Reconstr Surg 2001;108:1471-8.  Back to cited text no. 4
Demir Z, Oktem F, Celebioğlu S. Rare case of intramasseteric cavernous hemangioma in a three-year-old boy: A diagnostic dilemma. Ann Otol Rhinol Laryngol 2004;113:455-8.  Back to cited text no. 5


  [Figure 1], [Figure 2]

This article has been cited by
1 A rare case of multiple benign tumors of gingiva in a 4 year old child
Pooja Ahluwalia Sethi,Sunaina Jodhka,Sumit Sethi,Jasleen Kaur,Rajiv Surendra Desai
Pediatric Dental Journal. 2018;
[Pubmed] | [DOI]


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article
    Article Figures

 Article Access Statistics
    PDF Downloaded192    
    Comments [Add]    
    Cited by others 1    

Recommend this journal