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  Table of Contents  
Year : 2016  |  Volume : 7  |  Issue : 3  |  Page : 222-223  

SkIndia Quiz 25: A solitary nodule on the right buttock

1 Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Department of Dermatology, Tufts Medical Center, Boston, MA, USA
3 Department of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran

Date of Web Publication13-May-2016

Correspondence Address:
Amir Feily
Department of Dermatology, Jahrom University of Medical Sciences, Jahrom
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5178.178134

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Granuloma faciale (GF) is a benign, chronic inflammatory disorder, characterized by reddish brown plaques with prominent follicular orifices and telangeictasia, usually occurring over the face. The condition often presents a problem in differential diagnosis. Herein we describe a case of GF with an unusual diascopic finding of an apple jelly appearance on diascopy.

Keywords: Apple jelly nodule, diascopy, granuloma faciale

How to cite this article:
Yaghoobi R, Afshar N, Aliabdi M, Ramirez-Fort MK, Feily A. SkIndia Quiz 25: A solitary nodule on the right buttock. Indian Dermatol Online J 2016;7:222-3

How to cite this URL:
Yaghoobi R, Afshar N, Aliabdi M, Ramirez-Fort MK, Feily A. SkIndia Quiz 25: A solitary nodule on the right buttock. Indian Dermatol Online J [serial online] 2016 [cited 2022 Jan 18];7:222-3. Available from: https://www.idoj.in/text.asp?2016/7/3/222/178134

   Report of a Case Top

A 31-year-old otherwise healthy female presented with a six month history of a slowly growing solitary nodule on her right buttock. On physical examination there was a solitary firm, fixed, red to violaceous nodule with a diameter of 5 mm × 8 mm on the right buttock [Figure 1]. The overlying skin appeared slightly eroded with some surface maceration. There was a history of occasional bleeding with minor trauma, but no history of tenderness was mentioned. Physical examination was unremarkable. The lesion was completely excised and sent for histological examination.
Figure 1: Solitary small red to violaceous nodule on the right buttock

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   Microscopic Findings and Clinical Course Top

Histological examination demonstrates a solitary, dilated, cystic, dermal nodule with papillary projections toward the luminal spaces. The lumina was lined with a double layer of cells consisting of an inner layer of secretory cells and an outer layer of small cuboidal cells. A portion of the luminal cells showed evidence of decapitation secretion. The tumor was completely separated from the epidermal surface [Figure 2],[Figure 3],[Figure 4].
Figure 2: Tumor is surrounded by a fibrous capsule of connective tissue and composed of cystic space and papillary projections (H and E, ×40)

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Figure 3: Cystic and tubular structures lined with double layer of cells (H and E, ×100)

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Figure 4: The inner columnar cells show evidence of active decapitation secretion. (H and E, ×400)

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   What Is Your Diagnosis? Top

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   References Top

Lee HJ, Lee D, Jung SY, Hong SK, Seo JK, Sung HS. Hidradenoma papilliferum occurring on the nasal skin. Ann Dermatol 2011;23:S254-7.  Back to cited text no. 1
Kim YJ, Lee JW, Choi SJ, Kim SJ, Kim YJ, Jeon YS, et al. Ectopic hidradenoma papilliferum of the breast: Ultrasound finding. J Breast Cancer 2011;14:153-5.  Back to cited text no. 2
Vang R, Cohen PR. Ectopic hidradenoma papilliferum: A case report and review of the literature. J Am Acad Dermatol 1999;41:115-8.  Back to cited text no. 3
Al-Faky YH, Al-Mosallam AR, Al-Sohaibani MO. Periocular hidradenoma papilliferum. Saudi J Ophthalmol 2009;23:211-3.  Back to cited text no. 4
Offidani A, Campanati A. Papillary hidradenoma: Immunohistochemical analysis of steroid receptor profile with a focus on apocrine differentiation. J Clin Pathol 1999;52:829-32.  Back to cited text no. 5


  [Figure 1], [Figure 2], [Figure 3], [Figure 4]


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