|THROUGH THE DERMOSCOPE
|Year : 2017 | Volume
| Issue : 2 | Page : 162-163
A dermoscopic diagnosis and activity evaluation of frontal fibrosing alopecia in an indian lady
Sidharth Sonthalia1, Abhijeet K Jha2, Pankaj K Tiwary2
1 Consultant Dermatologist and Dermatosurgeon, SKINNOCENCE: The Skin Clinic, Gurgaon, Haryana, India
2 Department of Dermatology and STD, Patna Medical College and Hospital, Patna, Bihar, India
|Date of Web Publication||16-Mar-2017|
SKINNOCENCE: The Skin Clinic, Gurgaon - 122 009, Haryana
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Sonthalia S, Jha AK, Tiwary PK. A dermoscopic diagnosis and activity evaluation of frontal fibrosing alopecia in an indian lady. Indian Dermatol Online J 2017;8:162-3
|How to cite this URL:|
Sonthalia S, Jha AK, Tiwary PK. A dermoscopic diagnosis and activity evaluation of frontal fibrosing alopecia in an indian lady. Indian Dermatol Online J [serial online] 2017 [cited 2021 Oct 27];8:162-3. Available from: https://www.idoj.in/text.asp?2017/8/2/162/202278
A 67-year-old postmenopausal lady presented with frontal scalp hair loss and loss of eyebrows of 1-year duration. Examination revealed frontal cicatricial alopecia with temporoparietal extension, peripheral perifollicular scaling, and eyebrow madarosis [Figure 1]. Polarized videodermoscopy (EScope; Nakoda, ×20) revealed honeycombing of the scalp skin and multiple white dots representing absence of follicular openings, follicular hyperkeratosis and plugging, perifollicular scaling, and erythema [Figure 2]. Cicatricial white patches were not seen. Some interfollicular scaling and erythema were present, suggestive of mild seborrheic dermatitis.
|Figure 1: (a) Cicatricial alopecia of the frontal scalp with temporoparietal extension and (b) eyebrow madarosis|
Click here to view
|Figure 2: Dermoscopy of the alopecic area revealing honeycombing of the scalp skin (white arrow), multiple white dots representing absence of follicular openings (black arrows), prominent follicular hyperkeratosis and plugging encompassing black dots (yellow arrows), perifollicular scaling (blue arrows), and perifollicular erythema (green arrow). In addition, a black dot without surrounding hyperkeratosis/plugging (pink arrow) and yellow dot (red arrow) are visible. (polarizing mode, ×20)|
Click here to view
Few scattered yellow and several black dots were appreciable [Figure 2]. Miniaturized or vellus hairs were absent. Histopathology revealed perifollicular lymphocytic infiltrate, papillary dermal fibroplasia, and focal replacement of follicles with early fibrotic changes [Figure 3], confirming the diagnosis of active frontal fibrosing alopecia (FFA).
|Figure 3: Histopathology revealing partial flattening of epidermal rete ridges, perifollicular lymphocytic infiltrate, papillary dermal fibroplasias, marked reduction in the number of hair follicles, and focal replacement of follicles with early fibrotic changes (H and E, ×100)|
Click here to view
FFA, a cicatricial alopecia typically encountered in post-menopausal women, is considered to be a distinct variant of lichen planopilaris. Trichoscopy conveniently differentiates between the causes of alopecia of the scalp margin as FFA, alopecia areata (AA), traction alopecia, and cicatricial marginal alopecia (CMA). While the trichoscopic features easily ruled out AA, lack of miniaturized hairs and fractured hair shafts excluded traction alopecia. The absence of follicular openings, absence of vellus hairs, presence of follicular hyperkeratosis and plugs, and perifollicular scales are dermoscopic hallmarks of FFA.,, Absence of cicatricial white patches and presence of perifollicular erythema further suggest disease activity.,, These typical dermoscopic features and the typical histopathology confidently ruled out CMA. Honeycombing of the scalp skin is a normal trichoscopic finding in the skin of color chronically exposed to sunlight. The most common trichoscopic features of FFA include absence of follicular openings, followed by follicular hyperkeratosis, perifollicular erythema, and follicular plugs. In this case, we also observed the presence of few scattered yellow and several black dots, an inconsistent and uncommon feature of FFA.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Kossard S, Lee MS, Wilkinson B. Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris. J Am Acad Dermatol 1997;36:59-66.
Rubegni P, Mandato F, Fimiani M. Frontal Fibrosing Alopecia: Role of Dermoscopy in Differential Diagnosis. Case Rep Dermatol 2010;2:40-5.
Fernández-Crehuet P, Rodrigues-Barata AR, Vañó-Galván S, Serrano-Falcón C, Molina-Ruiz AM, Arias-Santiago S, et al
. Trichoscopic features of frontal fibrosing alopecia: Results in 249 patients. J Am Acad Dermatol 2015;72:357-9.
Duque-Estrada B, Tamler C, Sodré CT, Barcaui CB, Pereira FB. Dermoscopy patterns of cicatricial alopecia resulting from discoid lupus erythematosus and lichen planopilaris. An Bras Dermatol 2010;85:179-83.
Toledo-Pastrana T, Hernández MJ, Camacho Martínez FM. Perifollicular erythema as a trichoscopy sign of progression in frontal fibrosing alopecia. Int J Trichol 2013;5:151-3.
] [Full text]
[Figure 1], [Figure 2], [Figure 3]