Indian Dermatology Online Journal

REVIEW ARTICLE
Year
: 2018  |  Volume : 9  |  Issue : 5  |  Page : 293--298

Systemic drug-induced chronic paronychia and periungual pyogenic granuloma


Uwe Wollina 
 Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany

Correspondence Address:
Uwe Wollina
Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital of the Technical University of Dresden, Friedrichstrasse 41, 01067 Dresden
Germany

Paronychia is a painful inflammatory disorder of the nail fold. Periungual pyogenic granuloma – a benign vascular tumor of the capillaries – can develop as a complication of paronychia. We report both, paronychia and periungual pyogenic granuloma, as possible adverse events during systemic drug-therapy. The following groups of systemic drugs have been considered: taxanes, epidermal growth factor-receptor (EGFR) inhibitors, EGFR tyrosine kinase inhibitors, tyrosine kinase inhibitors, inhibitors of MEK/ERK, BRAF inhibitors, CD20 antagonists, vascular endothelial growth factor inhibitors, and retinoids. Recommendations for prevention and treatment are given. Since paronychia is a painful inflammatory disorder that has a negative impact on daily activities, early recognition and adequate treatment improve adhesion to treatment and quality of life.


How to cite this article:
Wollina U. Systemic drug-induced chronic paronychia and periungual pyogenic granuloma.Indian Dermatol Online J 2018;9:293-298


How to cite this URL:
Wollina U. Systemic drug-induced chronic paronychia and periungual pyogenic granuloma. Indian Dermatol Online J [serial online] 2018 [cited 2021 May 9 ];9:293-298
Available from: https://www.idoj.in/article.asp?issn=2229-5178;year=2018;volume=9;issue=5;spage=293;epage=298;aulast=Wollina;type=0