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REVIEW ARTICLE |
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Livedo reticularis: A review of the literature  |
p. 315 |
Vijaya Veeranna Sajjan, Snehal Lunge, Manjunathswamy Basavapuruda Swamy, Ashok Maharudrayya Pandit DOI:10.4103/2229-5178.164493 PMID:26500860Livedo reticularis (LR) is a cutaneous physical sign characterized by transient or persistent, blotchy, reddish-blue to purple, net-like cyanotic pattern. LR is a benign disorder affecting mainly middle-aged females, whereas livedo racemosa (LRC) is pathologic, commonly associated with antiphospholipid antibody syndrome. This article aims to review the causes of LR and LRC along with the evaluation and management. |
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ORIGINAL ARTICLES |
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Role of C-reactive protein as a marker of disease severity and cardiovascular risk in patients with psoriasis |
p. 322 |
Asha Ramay Vadakayil, Sukumar Dandekeri, Srinath M Kambil, Neema M Ali DOI:10.4103/2229-5178.164483 PMID:26500861Background: There is a paucity of studies addressing the elevation of C-reactive protein (CRP) among psoriatic patients and the role of this marker in assessment of disease severity and association with cardiovascular diseases (CVDs). Objective: To assess the difference in CRP levels between psoriatic patients and healthy population and to determine their role in disease severity. Also to compare CRP levels in psoriatic patients with and without the metabolic syndrome. Materials and Methods: A total of hundred patients with chronic plaque psoriasis and an equal number of age- and gender-matched healthy controls were enrolled in the study over a period of one year. Serum CRP levels of both cases and controls were estimated. Metabolic syndrome was identified among psoriasis patients using National Cholesterol Education Program's Adult Panel III (ATP III) guidelines. Clinical activity of psoriasis was evaluated using Psoriasis Area and Severity Index Score. Results: Patients with psoriasis reported significantly higher levels of CRP than healthy controls (P value 0.001). Patients with severe disease had significantly higher levels of CRP (P value < 0.003). Elevated level of CRP was observed among psoriatic patients with the metabolic syndrome than patients without the metabolic syndrome and the difference was statistically significant (P value = 0.001). Conclusion: CRP may be considered as a useful marker of psoriasis severity that could be used to monitor psoriasis and its treatment. Elevated levels of CRP may be an independent risk factor for CVD in patients with psoriasis. |
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Narrowband UVB phototherapy in pityriasis rosea |
p. 326 |
Vijayeeta Jairath, Madan Mohan, Nidhi Jindal, Paritosh Gogna, Clarify Syrty, Priyadarshini Mookalamada Monnappa, Sarabjit Kaur, Manu Sehrawat DOI:10.4103/2229-5178.164480 PMID:26500862Objective: Pityriasis rosea (PR) is an acute self-limiting disease. Despite vigorous efforts by generations of researchers since nearly 150 years, present treatment modalities for PR are not very gratifying. Ultraviolet radiation has been recommended in PR, although only a few studies validate this proposal. This study was conducted to explore the therapeutic effect of NBUVB on the symptoms, course, and severity of PR. Materials and Methods: This study involved a hundred patients who were randomly divided into two groups, using computer-generated randomization chart. Group A underwent treatment with fixed dose NBUVB of 250 mJ/cm2 three times (nonconsecutive) a week for 4 weeks. Group B formed the placebo group who did not receive any treatment. The two groups were compared with each other for the intensity of pruritis, course and duration of disease, and PR severity score (PRSS). Results: The t values of improvement in PRSS score in Group A (t = 12.796) were higher as compared with that in Group B (t = 10.066). Similarly, the t value of the pruritus scale in Group A (t = 7.758) was higher than Group B (t = 5.754) indicating the symptomatic improvement in itching. Conclusion: Fixed-dose NBUVB phototherapy resulted in marked improvement in the severity and symptoms of the disease as quantitatively assessed by PRSS. |
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CASE REPORTS |
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Kindler syndrome with palmoplantar hyperhidrosis and blonde hair |
p. 330 |
Anshul Maheshwari, Daulat Ram Dhaked, Deepak K Mathur, Puneet Bhargava DOI:10.4103/2229-5178.164482 PMID:26500863Kindler syndrome (KS) is a very rare genodermatosis characterized by acral blistering starting in infancy along with photosensitivity, progressive poikiloderma, cutaneous atrophy, and a variable degree of mucosal involvement. A large number of other cutaneous and extracutaneous features have been described, which aid in diagnosing it. Generally KS has been found to be associated with hypohidrosis/anhidrosis. We herein present a rare case of KS with unique features. |
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Lichen striatus with onychodystrophy in an infant |
p. 333 |
Shilpa Y Krishnegowda, Sudhir Kumar Ninga Reddy, Periswamy Vasudevan DOI:10.4103/2229-5178.164489 PMID:26500864Lichen striatus with nail involvement is rare and is often unnoticed. Nail changes are often nonspecific but they are usually localized to one portion of the nail. Also single nail involvement and presence of skin lesions near the nail are often noticed. We report the case of an infant with lichen striatus and nail involvement. |
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Ecthyma gangrenosum in a previously healthy patient |
p. 336 |
Ilkay Bozkurt, Esra Pancar Yuksel, Mustafa Sunbul DOI:10.4103/2229-5178.164479 PMID:26500865Ecthyma gangrenosum is a rare skin infection caused by Pseudomonas aeruginosa. It is usually seen in immunocompromised and critically ill patients. We report one such case in a previously healthy 20-year old male. Ecthyma gangrenosum can occur in healthy patients without bacteremia. |
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Penoscrotal porokeratosis: A distinct entity |
p. 339 |
Rajiv Joshi, Yatin Jadhav DOI:10.4103/2229-5178.164487 PMID:26500866A 26-year-old man presented with five months history of redness associated with itching and burning over the scrotum and shaft of the penis with a persistent rash on those sites. There had been no response to topical steroid and antifungal creams. Clinical examination revealed a large well-circumscribed erythematous plaque with a thready raised border with a tiny groove at its summit that involved almost two-thirds of the ventral part of the shaft of the penis. Ill-defined erythema with a granular surface was seen over the anterior scrotal skin. A 4 mm punch biopsy of the plaque on the penile shaft revealed multiple cornoid lamellae located adjacent to one another. The patient was treated with topical emollients. Follow up after four months revealed almost complete resolution of the plaque on the penile shaft. Penoscrotal porokeratosis appears to be a distinct entity in the family of porokeratotic diseases, described only in young males in their twenties with involvement of the penile shaft and anterior scrotum with severe burning and itching and histologically associated with multiple cornoid lamellae. It may represent an unusual epidermal porokeratotic reaction pattern and may be a self-resolving condition. |
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Extragenital lichen sclerosus et atrophicus along the lines of Blaschko |
p. 342 |
Nilofar G Diwan, Pragya A Nair DOI:10.4103/2229-5178.164486 PMID:26500867Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis of unknown etiology. Extragenital involvement is uncommon and commonly affects the neck, shoulders, and upper portion of the trunk. It is predominant in women with a male-to-female ratio of 1:6 and occurs at any age. Linear pattern along the lines of Blaschko are seen. There is no cure for LSA. Topical corticosteroids and calcineurin inhibitors, such as tacrolimus, pimecrolimus, PUVA antimalarial agents, and topical retinoids have been tried with varying results. A case of a 33-year-old man with LSA over right lower limb along the lines of Blasckho is reported here. |
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Linear Darier's disease: A case with bilateral presentation |
p. 345 |
Anal Jyoti Bordoloi, Khagendra Narayan Barua DOI:10.4103/2229-5178.164485 PMID:26500868Darier's disease is an autosomal dominant genodermatosis characterized by a persistent eruption of hyperkeratotic greasy papules mainly over the seborrheic sites of the body, usually associated with nail abnormalities and sometimes with mucous membrane lesions. The lesions typically occur in the younger age group and are associated with pruritus. We report here an atypical case of Linear Darier's disease with bilateral presentation in a middle-aged adult that could be confused with conditions such as lichen planus, inflammatory linear verrucous epidermal nevus, and wart. |
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Unilateral hypertrophic skin lesions, hemimegalencephaly, and meningioma: The many faces of Proteus syndrome |
p. 348 |
Niharika R Lal, Debabrata Bandyopadhyay, Asim K Sarkar DOI:10.4103/2229-5178.164477 PMID:26500869Proteus syndrome is a rare condition with a wide spectrum of abnormalities. It is characterized by hamartomatous malformations involving multiple organs. Serious complications may ensue, such as pulmonary embolism, cystic lung disease, and various neoplasms such as parotid adenomas, ovarian cystadenomas, and meningiomas. We report here a case of Proteus syndrome in a 21-year-old woman who had facial hemihypertrophy, cerebriform plantar hyperplasia, hemimegalencephaly, and meningioma for the rarity of the entity. |
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Atrichia congenita |
p. 352 |
Chandraprakash Chouhan, Rajeev Khullar, Pankaj Rao, Ramesh Raidas DOI:10.4103/2229-5178.164478 PMID:26500870Atrichia congenita is a rare genodermatoses is characterized by a mutation of the human hairless (HR) gene on chromosome 8p22. There is loss of scalp hair between one to six months of age, after which no growth occurs. Eyebrow, eyelash, and body hair may also be sparse or absent; patients may have a few pubic and axillary hairs. The condition may present in isolation or along with other defects. |
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CASES FROM ACKERMAN ACADEMY |
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A rubbery dermal nodule |
p. 354 |
Soren Craig-Muller, Dirk M Elston DOI:10.4103/2229-5178.164464 PMID:26500871 |
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An indurated plantar plaque with surface nodularity |
p. 356 |
Soren Craig-Muller, Dirk M Elston DOI:10.4103/2229-5178.164466 PMID:26500872 |
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LETTERS TO EDITOR |
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Nevus depigmentosus with unilateral bluish sclera, a rare entity |
p. 358 |
Abhijeet Kumar Jha, Rajesh Sinha, Smita Prasad DOI:10.4103/2229-5178.164491 PMID:26500873 |
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Phaeohyphomycosis presenting as a solitary nodulocystic lesion in a renal transplant patient |
p. 359 |
Gopinathan Nanda Kumar, Sukumaran Pradeep Nair DOI:10.4103/2229-5178.164468 PMID:26500874 |
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Neutrophilic dermatosis of the dorsal hands: A rare unilateral presentation |
p. 361 |
Sarvesh S Thatte, Asok Aggarwal DOI:10.4103/2229-5178.164490 PMID:26500875 |
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Pronounced skin folds with finger clubbing |
p. 362 |
Sweta Rambhia, Bhanu Prakash DOI:10.4103/2229-5178.164492 PMID:26500876 |
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Kaposi varicelliform eruption |
p. 364 |
Rita V Vora, Abhishek P Pilani, Nidhi B Jivani, Rahul K Kota DOI:10.4103/2229-5178.164484 PMID:26500877 |
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Liposomal doxorubicin-induced palmoplantar erythrodysthesia syndrome |
p. 366 |
Nidhi Yadav, Bhushan Madke, Sumit Kar, Kameshwar Prasad DOI:10.4103/2229-5178.164488 PMID:26500878
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SKINDIA QUIZ 20 |
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SkIndia Quiz 20: A case of multiple nodules on forearm |
p. 369 |
Ruby Venugopal, Michael John, Rajesh Verma, Biju Vasudevan, Prabal Deb, Anuj Bhatnagar DOI:10.4103/2229-5178.160324 PMID:26500879 |
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THROUGH THE LENS |
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Vulval elephantiasis |
p. 371 |
Arun Prasath Palanisamy, Kamalakannan Kutuwa Kanakaram, Sivasubramanian Vadivel, Srivenkateswaran Kothandapany DOI:10.4103/2229-5178.164470 PMID:26500880 |
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Sister Mary Joseph's nodule |
p. 372 |
Shikha Goyal, Pramod K Julka DOI:10.4103/2229-5178.164472 PMID:26500881 |
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Soft pink nodules on the scalp |
p. 373 |
S Pradeep Nair DOI:10.4103/2229-5178.164473 PMID:26500882 |
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Crab louse |
p. 375 |
Arun Prasath Palanisamy, Kamalakannan Kutuwa Kanakaram, Sivasubramanian Vadivel, Srivenkateswaran Kothandapany DOI:10.4103/2229-5178.164475 PMID:26500883 |
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Axillary syringomas mimicking Fox–Fordyce disease |
p. 376 |
Gillian Roga, Ishwar Bhat DOI:10.4103/2229-5178.164476 PMID:26500884 |
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