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EDITORIAL |
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Bidding adieu |
p. 379 |
Shyam Verma DOI:10.4103/2229-5178.169734 PMID:26753135 |
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ORIGINAL ARTICLES |
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Diagnostic value of Tzanck smear in various erosive, vesicular, and bullous skin lesions  |
p. 381 |
Atiya Yaeen, Qazi Masood Ahmad, Anjum Farhana, Parveen Shah, Iffat Hassan DOI:10.4103/2229-5178.169729 PMID:26751561Background: Cutaneous cytology has long been shown to be useful in the diagnosis of several erosive, vesicular, and bullous skin lesions. The Tzanck smear although an old tool, still remains a simple, rapid, easily applied, and inexpensive test for these skin lesions. Aims and Objectives: The aim of this study was to evaluate the diagnostic value of Tzanck smear by determining its sensitivity and specificity in various erosive, vesicular, and bullous skin lesions. Materials and Methods: One hundred and forty-two patients with erosive, vesicular, and/or bullous skin lesions were included in the study. Four groups of disorders were identified: infections, immunologic disorders, genodermatosis, and spongiotic dermatitis. All the study cases were evaluated by Tzanck smear. Definitive diagnosis was established by standard diagnostic techniques (including when appropriate, viral serology, bacterial culture, histopathology, direct immunoflourescence). Results: The sensitivity and specificity of cytologic findings was respectively 86.36% and 91.30% for viral infections; for bacterial infections, it was 85.7% and 66.6%. The sensitivity and specificity of Tzanck smear was respectively 85.0% and 83.33% for pemphigus; for bullous pemhigoid it was 11.11% and 100.0%. Tzanck smear sensitivity in genodermatoses was 100%. The sensitivity and specificity of the test in spongiotic dermatitis could not be calculated due to an insufficient number of patients. Conclusion: The Tzanck smear is a quick and reliable tool for the evaluation of various erosive and vesiculobullous skin lesions. |
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Clinical study of cutaneous leishmaniasis in the Kashmir Valley |
p. 387 |
Gh Mohiuddin Wani, Sheikh Manzoor Ahmad, Bilques Khursheed DOI:10.4103/2229-5178.169732 PMID:26753136Background: Cutaneous leishmaniasis (CL) is an infectious disease of tropical and semitropical areas of the world. The cold and harsh winter conditions of the Kashmir Valley do not favor the survival and growth of the Leishmania parasite or its vector, the sand fly, and the disease was until now practically unheard of in the Kashmir Valley. Aims: There has been a recent rise in the number of cases of CL in the Kashmir Valley. Against this background, the present study was taken up to describe the epidemiology, clinical features, and management outcomes of CL in the Kashmir Valley, where it represents a new phenomenon. Materials and Methods: Patients with direct smear-confirmed CL were evaluated. For each patient, we noted age, gender, geographical origin, stays in endemic areas, clinical aspects, number, site and size of lesions, treatment, and outcome. All the infected patients were treated with sodium stibogluconate. The dose, route of administration, adverse effects, and the clinical response in each patient was noted down. Results: Eighteen patients, 11 males (61.12%) and 7 females (38.88%) were studied. The age of the patients ranged from 3 to 60 years (mean age 29.8). The majority of our patients (16, 88.9%) belonged to two hilly areas, Uri and Karnah. Duration of the disease ranged from a minimum of 1 month to a maximum of 18 months (mean duration 4.6 months). Lesions in most of our patients (16, 88.9%) were located on the face including the lip and nose. The size of lesions varied from 4 to about 50 mm (average 2-3 cm). Most of our patients (13, 73.3%) had only a single lesion and a few (5, 26.7%) had two or three lesions. The clinical type of lesion in most of our patients (16, 88.9%) was noduloulcerative, only two (11.1%) had nodular (nonulcerative) lesions. Sixteen patients; all with facial lesions were treated with intravenous sodium stibogluconate. A complete response was seen in 14 (87%), without any major adverse effect. Two adult patients with extrafacial lesions were treated with four doses of weekly intralesional injections of sodium stibogluconate. A complete response was seen in both, without any major adverse effect. Conclusion: The emergence of CL in this nonendemic area is of great epidemiological importance. Because no parasite isolation and characterization was carried out, further epidemiological studies and taxonomic differentiation of the species are required. |
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CASE REPORTS |
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Conidiobolomycosis: A case report of rare fungal infection from the eastern India |
p. 393 |
Somashree Dutta, Somenath Sarkar, Uttam Linka, Sujata Dora DOI:10.4103/2229-5178.169715 PMID:26753137Conidiobolomycosis is a rare chronic subcutaneous mycosis of nose and paranasal sinuse predominately affects the middle age men in tropical countries. It is caused by a saprophytic fungus "Conodiobolus coronatus", which can survives in soils and dried vegetables for long period of time. C. coronatus belongs to the class Zygomycetes, order Entomophthorales. It is a fungus composed of thick- walled, short hyphae that grows at temperatures of 30 to 37 degrees C. Here we report a case of conidiobolomycosis in a 55- year- old farmer presented with a subcutaneous swelling over the left side of nose extending to left cheek. |
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Carcinoma erysipeloides as a presenting feature of breast carcinoma: A case report and brief review of literature |
p. 396 |
Ali Al Ameer, Maryam Imran, Feroze Kaliyadan, Rajan Chopra DOI:10.4103/2229-5178.169724 PMID:26753138Carcinoma erysipeloides (CE) is an uncommon but distinctive form of cutaneous metastasis that usually manifests clinically as a fixed erythematous patch or plaque resembling cellulitis or erysipelas. The inflamed area may show a distinct raised edge at the periphery and also edema secondary to lymphatic obstruction. Histologically, dense carcinoma cells in the dermal vascular channels and dense perivascular lymphocytic infiltrate may be seen. CE may rarely be the first sign of “silent” tumor of breast. We report a case of a 52-year-old married lady who presented with a three months history of pruritic erythematous patches over the left side of the breast that was resistant to all topical treatments and was diagnosed as erysipeloid breast carcinoma. |
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Kaposi's varicelliform eruption: A case series |
p. 399 |
Bruno Ferrari, Vanina Taliercio, Paula Luna, María Eugenia Abad, Margarita Larralde DOI:10.4103/2229-5178.169714 PMID:26753139Kaposi's varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. It concomitantly occurs with pre-existing skin conditions, mostly atopic dermatitis, so it is predominately found in children. We present a case series that includes four adults, familial cases, and previously healthy patients. We also highlight clinical features, associations and therapeutic options. |
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Naegeli-Franceschetti-Jadassohn syndrome: A rare case |
p. 403 |
Bela J Shah, Ashish K Jagati, Neha P Gupta, Suyog S Dhamale DOI:10.4103/2229-5178.169712 PMID:26753140Naegeli-Franceschetti-Jadassohn Syndrome (NFJS) is a rare, autosomal dominant inherited form of ectodermal dysplasia, caused by mutation in the KRT14 gene. We report here a case of NFJS in a 27-year-old male who presented with reticulate hyperpigmentation over skin, dental changes, absence of dermatoglyphics, hypohidrosis, and hair changes. |
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Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
p. 407 |
Radhakrishnan Subramaniyan, Rajagopal Ramachandran, Gnanasekaran Rajangam, Navya Donaparthi DOI:10.4103/2229-5178.169743 PMID:26753141Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide. |
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Subcutaneous entomophthoromycoses |
p. 410 |
Tadepalli Karuna, Dinesh P Asati, Debasis Biswas, Shashank Purwar DOI:10.4103/2229-5178.169730 PMID:26753142Subcutaneous entomophthoromycoses is a zygomycosis caused by Basidiobolus ranarum that is endemic in southern India. We report the case of a 63-year-old male from central India who presented with a nontender subcutaneous hyperpigmented plaque on his leg with mild discharge that yielded Basidiobolus ranarum. |
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Gianotti-Crosti Syndrome following immunization in an 18 months old child |
p. 413 |
Thirunavukkarasu Arun Babu, Avinash Arivazhahan DOI:10.4103/2229-5178.169713 PMID:26751677Gianotti-Crosti syndrome (GCS) is an uncommon dermatological condition characterized by distinct, self-limiting, symmetrical, erythematous, papulovesicular eruptions distributed mainly on the extremities, buttocks and face in young children. Although GCS is commonly attributed to viral infections, vaccinations too can rarely precipitate this condition. We report a rare case of GCS following diptheria, pertussis, and tetanus (DPT) and oral polio immunisation in an 18-month-old child along with a review of similar vaccine-induced GCS cases reported in the literature. |
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CASES FROM ACKERMAN ACADEMY |
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Dermatopathology quiz: Cerebriform papules of the scrotum |
p. 416 |
Cassondra Andreychik, Leonard J Bernstein, Dirk Elston DOI:10.4103/2229-5178.169719 PMID:26751781 |
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Asymptomatic erythematous plaque |
p. 419 |
Olga V Udovenko, John R Griffin, Dirk M Elston DOI:10.4103/2229-5178.169721 PMID:26753143 |
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Multiple nodules on the sole of the foot |
p. 422 |
Alyssa J Miceli, Jacqueline M Junkins-Hopkins, Dennis C Polley, Dirk M Elston DOI:10.4103/2229-5178.169720 PMID:26753144Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations. |
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MUSINGS, OPINIONS, TIPS AND EXPERIENCES |
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Global leprosy program: Does it need uniform-multi-drug therapy now? |
p. 425 |
P Narasimha Rao, Sunil Dogra, Sujai Suneetha DOI:10.4103/2229-5178.169735 PMID:26753145 |
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DRUG PROFILE |
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Aspirin in dermatology: Revisited |
p. 428 |
Aditya Kumar Bubna DOI:10.4103/2229-5178.169731 PMID:26753146Aspirin has been one of the oldest drugs in the field of medicine, with a wide range of applications. In dermatology, aspirin has shown benefit in a variety of disorders. Recently, reduction of melanoma risk with aspirin has been demonstrated. Although an analgesic to begin with, aspirin has come a long way; after cardiology, it is now found to be useful even in dermatology. |
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LETTERS TO THE EDITOR |
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Aneurysmal benign fibrous histiocytoma presenting as a giant acrochordon on thigh |
p. 436 |
Anupam Das, Anirban Das, Debabrata Bandyopadhyay, Vivek Mishra, Abanti Saha DOI:10.4103/2229-5178.169740 PMID:26753147 |
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Hutchinson-Gilford progeria syndrome |
p. 438 |
Amar Singh Bhukya, Bellum Siva Nagi Reddy DOI:10.4103/2229-5178.169733 PMID:26753148 |
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Necrotizing fasciitis associated with systemic lupus erythematosus in a child |
p. 441 |
Sahana M Srinivas, Alkarani T Patil, Gowri Shankar, Keshavmurthy M Lakshmikantha, Munirathnam Govindraj DOI:10.4103/2229-5178.169737 PMID:26753149 |
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A postoperative case of carcinoma erysipeloides arising from ductal carcinoma of the breast |
p. 443 |
Shankar Sathish, Talari Srinivas Rajashekar, Bittanakurike Narasappa Raghavendra, Gurumurthy Rajesh DOI:10.4103/2229-5178.169710 PMID:26753150 |
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Rituximab therapy in a case of pemphigus vulgaris triggering herpes simplex infection at varied sites |
p. 444 |
Kiran K Chotaliya, Richa Gupta, Yogesh S Marfatia DOI:10.4103/2229-5178.169722 PMID:26753151 |
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Acute generalized exanthematous pustulosis due to meropenem: An unusual side effect of a commonly used drug |
p. 446 |
Loknath Ghoshal, Saumen Nandi, Aritra Sarkar, Sudip Das DOI:10.4103/2229-5178.169711 PMID:26751943 |
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Granuloma faciale |
p. 448 |
Deepti Kataria, Swagata Tambe, Chitra S Nayak DOI:10.4103/2229-5178.169741 PMID:26752060 |
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COMMENTARY |
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Granuloma faciale: A master masquerader? |
p. 450 |
Najeeba Riyaz PMID:26752188 |
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LETTER TO THE EDITOR |
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Porokeratosis and malignant melanoma: A causal or incidental association? |
p. 451 |
Leonor Neto Lopes, Ana Isabel Gouveia, Luís Soares-Almeida, Manuel Sacramento-Marques, Paulo Filipe DOI:10.4103/2229-5178.169736 PMID:26753152 |
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COMMENTARY |
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Porokeratosis and malignancy: Incidental or causal association? |
p. 452 |
Najeeba Riyaz PMID:26753153 |
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SKINDIA QUIZ |
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SkIndia Quiz 21: Recurrent papulonodular lesions on elbows, fingers and lower leg |
p. 454 |
Anupam Das, Indrani Das, Anupama Ghosh, Piyush Kumar, Nilay K Das, Ramesh C Gharami DOI:10.4103/2229-5178.164579 PMID:26753154 |
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THROUGH THE LENS |
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Linear rays of depigmentation along lymphatics after intralesional corticosteroid therapy |
p. 456 |
Kameshwar Prasad, Bhushan Madke, Sumit Kar, Amit K Sinha, Nidhi Yadav DOI:10.4103/2229-5178.169728 PMID:26753155 |
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Extensive terra firma forme dermatosis [TFFD]: A rare presentation |
p. 458 |
Komal Panchal, Neha Bhalla, Pranjal Salunke, Hemangi Jerajani DOI:10.4103/2229-5178.169742 PMID:26752293 |
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Acrokeratoelastoidosis |
p. 460 |
Kinjal D Rambhia, Uday S Khopkar DOI:10.4103/2229-5178.169718 PMID:26753156 |
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Acute and dramatic saxophone penis |
p. 462 |
Carlota Gutiérrez García-Rodrigo, Lidia Maroñas-Jimenéz, Diana Menis, Hugo Larráin, Lara Angulo Martínez DOI:10.4103/2229-5178.169726 PMID:26752411We present a case of intense genital swelling because of a hereditary angioedema. This rare disease should be included in the differential diagnosis of acute and asymptomatic genital edema, because it may prevent future potentially life-threatening episodes of visceral angioedema. |
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Urticaria pigmentosa |
p. 464 |
Resham J Vasani, Sudhir V Medhekar DOI:10.4103/2229-5178.169727 PMID:26752589 |
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Scrotal calcinosis |
p. 466 |
Sweta Rambhia, Bhanu Prakash DOI:10.4103/2229-5178.169725 PMID:26753157 |
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A seemingly insignificant lesion |
p. 467 |
Anahita Sadeghi, Mohammad Biglari DOI:10.4103/2229-5178.169723 PMID:26753158 |
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