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Access statistics : Table of Contents
2016| March-April | Volume 7 | Issue 2
Online since
March 4, 2016
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REVIEW ARTICLE
Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review
Alok Kumar Sahoo, Rahul Mahajan
March-April 2016, 7(2):77-86
DOI
:10.4103/2229-5178.178099
PMID
:27057486
The prevalence of superficial mycotic infection worldwide is 20–25% of which dermatophytes are the most common agents. Recent developments in understanding the pathophysiology of dermatophytosis have confirmed the central role of cell-mediated immunity in countering these infections. Hence, a lack of delayed hypersensitivity reaction in presence of a positive immediate hypersensitivity (IH) response to trichophytin antigen points toward the chronicity of disease. Diagnosis, though essentially clinical should be confirmed by laboratory-based investigations. Several new techniques such as polymerase chain reaction (PCR) and mass spectroscopy can help to identify the different dermatophyte strains. Management involves the use of topical antifungals in limited disease, and oral therapy is usually reserved for more extensive cases. The last few years have seen a significant rise in the incidence of chronic dermatophyte infections of skin which have proven difficult to treat. However, due to the lack of updated national or international guidelines on the management of tinea corporis, cruris, and pedis, treatment with systemic antifungals is often empirical. The present review aims to revisit this important topic and will detail the recent advances in the pathophysiology and management of tinea corporis, tinea cruris, and tinea pedia while highlighting the lack of clarity of certain management issues.
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74,061
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12
EDITORIAL
The menace of chronic and recurrent dermatophytosis in India: Is the problem deeper than we perceive?
Sunil Dogra, Shraddha Uprety
March-April 2016, 7(2):73-76
DOI
:10.4103/2229-5178.178100
PMID
:27057485
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1,285
5
CASE REPORTS
Clinically granulomatous cheilitis with plasma cells
Somenath Sarkar, Sarmistha Ghosh, Dipayan Sengupta
March-April 2016, 7(2):96-98
DOI
:10.4103/2229-5178.178094
PMID
:27057489
Plasma cell cheilitis, also known as plasma cell orificial mucositis is a benign inflammatory condition clinically characterized by erythematous plaque on lips that may be ulcerated. Histopathologically it is characterized by dense plasma cell infiltrates in a band-like pattern in dermis, which corresponds to Zoon's plasma cell balanitis. On the other hand, granulomatous cheilitis, as a part of orofacial granulomatosis, manifests as sudden diffuse or nodular swelling involving lip and cheek. Initial swelling is soft to firm, but with recurrent episodes swelling gradually become firm rubbery in consistency. We hereby report a case of cheilitis in a 52-year-old man with diffuse swelling involving lower lip, which clinically resembles granulomatous cheilitis, but histopathological examination showed diffuse infiltrate of plasma cells predominantly in upper and mid-dermis.
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4,509
349
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THROUGH THE LENS
Hailey-Hailey disease
Nidhi Yadav, Bhushan Madke, Sumit Kar, Kameshwar Prasad, Nitin Gangane
March-April 2016, 7(2):147-148
DOI
:10.4103/2229-5178.178090
PMID
:27057511
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3,104
468
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CASE REPORTS
Hepatitis B, interferon, and acne fulminans in a young girl
Sandeep Arora, Ajay Malik, Dharmendra Kumar, Neha Sodhi
March-April 2016, 7(2):93-95
DOI
:10.4103/2229-5178.178080
PMID
:27057488
Acne fulminans (AF) is a very rare severe form of acne seen in young males, characterized by a sudden and explosive onset of hemorrhagic pustules and ulceration on the trunk, systemic features in the form of fever, polyarthropathy, malaise, erythema nodosum and painful osteolytic bone involvement with leukocytosis, and an elevated erythrocyte sedimentation rate. Conventional treatment of AF includes corticosteroids or immunosuppressive agents for the initial phase followed by isotretinoin. Active hepatitis B infection with a high viral load precludes the administration of any immunosuppressive drugs. We present the case of an 18-year-old girl with a history of occasional acne who presented with AF of sudden onset following administration of interferon-alpha-2a for her recently detected hepatitis B infection. Management of hepatitis B was withheld in view of her general condition. The patient was managed with low dose isotretinoin with subsidence of lesions. AF in a young female precipitated by interferon and its management with isotretinoin in the presence of active hepatitis B infection make the case unique.
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ORIGINAL ARTICLE
Efficacy of narrowband ultraviolet B phototherapy and levels of serum vitamin D3 in psoriasis: A prospective study
Aditi Gupta, Trilok Chand Arora, Ankur Jindal, Ajeet Singh Bhadoria
March-April 2016, 7(2):87-92
DOI
:10.4103/2229-5178.178081
PMID
:27057487
Introduction:
Narrowband ultraviolet B phototherapy (NBUVB) is safe and effective treatment for psoriasis. Vitamin D plays an important role in pathogenesis of psoriasis. It is known that psoriasis patients have low serum 25(OH)D levels, which increase after NBUVB. We assessed serum 25(OH)D levels, its correlation with Psoriasis Area and Severity Index (PASI), and the effect of NBUVB on 25(OH)D levels among Indian psoriasis patients.
Materials and Methods:
A prospective study comprising 30 adults with psoriasis with no major comorbidities (PASI > 10 and off-therapy >4 weeks) was conducted. PASI was estimated at baseline among patients and repeated after receiving 12 weeks of NBUVB therapy. Thirty age and gender-matched healthy controls were recruited to compare 25(OH)D levels at baseline and at 12 weeks. Patient demographic parameters, treatment dose, duration, side effects, and its impact on 25(OH)D levels and PASI were serially evaluated.
Results:
A total of 30 patients presenting with psoriasis and 30 healthy controls were enrolled in the study. Mean baseline PASI (M: F =19:11) among patients with mean age 36.8 (±7.7) years was 20.5 (±6.3) and all patients were either 25(OH)D deficient (
n
= 14) or insufficient (
n
= 16). Their baseline 25(OH)D levels were significantly lower than controls (25.93 nmol/L vs 47.54 nmol/L;
P
< 0.001). After NBUVB therapy (average cumulative dose 20.76 ± 7.1 J/cm
2
; average treatment sessions 32.57 ± 1.9), there was a significant improvement in PASI as well as 25(OH)D (
P
< 0.05). There was no correlation between the mean improvement in PASI and 25(OH)D after 12 weeks of therapy. Twelve (40%) patients had therapy-related side effects [pruritus (
n
= 8), erythema (
n
= 4)], none had major side effects.
Conclusion:
Improvement in PASI and serum 25(OH)D levels after NBUVB in psoriasis is significant but poorly correlated with each other. Vitamin D may not be the lone mediator of the therapeutic effects of NBUVB on psoriasis.
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2
CASE REPORTS
Pyogenic granuloma underlying cutaneous horn in a young boy
Pragya A Nair, Rahul Krishna S Kota, Abhisheik P Pilani
March-April 2016, 7(2):114-116
DOI
:10.4103/2229-5178.178086
PMID
:27057494
Cutaneous horn is an elongated, keratinous projection that usually occurs over the sun-exposed areas. It is a clinical diagnosis and may overlie any benign, premalignant, or malignant conditions. Treatment includes wide surgical excision with careful histological examination to exclude a focus of malignancy. An unusual case of a pyogenic granuloma presenting as cutaneous horn on the lower lip in an 11-year-old boy is presented here.
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2,542
210
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Reactive perforating collagenosis
Sandeep Arora, Ajay Malik, Anil Balki
March-April 2016, 7(2):139-140
DOI
:10.4103/2229-5178.178084
PMID
:27057507
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2,262
287
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CASE REPORTS
Atypical cases of Dowling-Degos disease
Kikkeri Narayanshetty Naveen, Sharatchandra B Athaniker, Spandana P Hegde, Rahul Shetty, Hanumanthayya Radha, Sadashivappa Sangam Parinitha
March-April 2016, 7(2):99-102
DOI
:10.4103/2229-5178.178096
PMID
:27057490
Dowling–Degos disease (DDD) is a rare autosomal dominant condition characterized by multiple, small, round pigmented macules usually arranged in reticular pattern, chiefly distributed in axillae and groins. Here we are reporting three atypical cases of DDD in a family. They had hypopigmented macules with typical features of DDD indicating generalized DDD. Histopathology confirmed the diagnosis. We present these three cases to stress the existence of generalized DDD phenotype in the Indian population.
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2,234
308
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LETTERS TO THE EDITOR
Generalized eruptive syringoma: A clinical dilemma
Abhijeet Kumar Jha, Rajesh Sinha, Smita Prasad, Ruchi Sinha
March-April 2016, 7(2):127-128
DOI
:10.4103/2229-5178.178082
PMID
:27057500
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2,250
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CASE REPORTS
Apocrine hidrocystoma arising from nevus sebaceous on the scalp
Cherukuri Tejaswi, Murugaiyan Rangaraj, Kaliaperumal Karthikeyan
March-April 2016, 7(2):111-113
DOI
:10.4103/2229-5178.178088
PMID
:27057493
Nevus sebaceous is a hamartoma with an uneventful course since birth but many benign or malignant tumors are known to develop in about one third of the patients. A 37-year-old woman with asymptomatic hairless raised lesion over the scalp since birth presented with change in the morphology of the lesions associated with itching and irritation since one month. On examination, multiple well-defined hyperpigmented verrucous plaques coalescing with each other were seen over the right parietal scalp associated with alopecia. A single well-defined soft skin-colored cystic swelling of size 1 × 2 cm was seen interspersed within the plaque. After a clinical diagnosis of nevus sebaceous, a biopsy of the cyst was done, which revealed a large cyst lined by columnar and myoepithelial cells in the dermis. The columnar cells at a few places showed “decapitation secretion” giving the impression of apocrine hidrocystoma. Post-excision of the cyst, biopsy of the entire nevus was done and the histopathological diagnosis correlated with the clinical diagnosis of nevus sebaceous. Apocrine hidrocystoma developing from a sebaceous nevus over the scalp is a rarity with only three other cases of it arising on the scalp being reported and none of them developed from a sebaceous nevus.
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2,258
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1
Elastosis perforans serpiginosa in a case of pseudoxanthoma elasticum: A rare association
Konakanchi Venkatachalam, Kavya Chennamsetty
March-April 2016, 7(2):103-106
DOI
:10.4103/2229-5178.178078
PMID
:27057491
Elastosis perforans serpiginosa (EPS), characterized by transepidermal elimination of fragmented elastic fibers, clinically presents as hyperkeratotic papules. EPS is classified into three types: (1) Idiopathic; (2) reactive, with associated connective tissue diseases such as pseudoxanthoma elasticum (PXE), Ehlers–Danlos syndrome, cutis laxa, Marfan syndrome, osteogenesis imperfecta, Down's syndrome; (3) the one that is induced by D-penicillamine. A rare association of EPS with PXE, which is primarily a defect of transmembrane transporter protein with accumulation of certain metabolic compounds and secondary calcification of elastic fibers has been documented in the literature. We report a case of PXE with associated lesions that were histopathologically compatible with EPS.
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1,989
251
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Annular elastolytic giant cell granuloma in association with Hashimoto's thyroiditis
Rishi Hassan, P Arunprasath, L Padmavathy, K Srivenkateswaran
March-April 2016, 7(2):107-110
DOI
:10.4103/2229-5178.178087
PMID
:27057492
Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized clinically by annular plaques with elevated borders and atrophic centers found mainly on sun-exposed skin and histologically by diffuse granulomatous infiltrates composed of multinucleated giant cells, histiocytes and lymphocytes in the dermis along with phagocytosis of elastic fibers by multinucleated giant cells. We report a case of AEGCG in a 50-year-old woman and is highlighted for the classical clinical and histological findings of the disease and its rare co-existence with Hashimoto's thyroiditis.
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1,865
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1
SKINDIA QUIZ
SkIndia Quiz 23: A swelling on the tongue
S Sudhakar, J Rocky, P Ramaswamy, B Smitha, Ch Sai Kiran
March-April 2016, 7(2):137-138
DOI
:10.4103/2229-5178.174341
PMID
:27057506
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1,841
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LETTERS TO THE EDITOR
Topical timolol maleate: An effectual and safe recourse for infantile hemangiomas
Yasmeen Jabeen Bhat, Atiya Yaseen, Iffat Hassan
March-April 2016, 7(2):124-125
DOI
:10.4103/2229-5178.178076
PMID
:27057498
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1,769
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THROUGH THE LENS
Cytodiagnostic copper pennies in chromoblastomycosis
Gopikrishnan Anjaneyan, Soumya Jagadeesan, Jacob Thomas
March-April 2016, 7(2):145-146
DOI
:10.4103/2229-5178.178085
PMID
:27057510
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1,700
213
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Solitary mastocytoma with positive Darier's sign
Brijesh Nair, Sidharth Sonthalia, Ishad Aggarwal
March-April 2016, 7(2):141-142
DOI
:10.4103/2229-5178.178091
PMID
:27057508
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1,628
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CASES FROM ACKERMAN ACADEMY
Irregular pigmented lesion on the genital area
Manuel Valdebran, Kruti Parikh, Deborah S Sarnoff, Dirk M Elston
March-April 2016, 7(2):117-118
DOI
:10.4103/2229-5178.178098
PMID
:27057495
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1,368
255
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A warty lesion on the penis
Kara Melissa T Torres, Dennis C Polley, Filamer Kabigting, Dirk M Elston
March-April 2016, 7(2):119-120
DOI
:10.4103/2229-5178.178097
PMID
:27057496
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1,219
202
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LETTERS TO THE EDITOR
Granuloma faciale
Manveen Kaur, Avninder Singh, Venkat Ramesh
March-April 2016, 7(2):130-132
DOI
:10.4103/2229-5178.178083
PMID
:27057502
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1,165
217
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THROUGH THE LENS
Urbach-Weithe disease (lipoid proteinosis): A classical presentation
Ankita Sangwan, Sarabjit Kaur, Vijay K Jain, Surabhi Dayal
March-April 2016, 7(2):143-144
DOI
:10.4103/2229-5178.178089
PMID
:27057509
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1,128
222
1
LETTERS TO THE EDITOR
Acute infectious purpura fulminans caused by group A β-hemolytic
Streptococcus
: An uncommon organism
Divya Gupta, Laxmisha Chandrashekar, Bheemanathi Hanuman Srinivas, Devinder Mohan Thappa
March-April 2016, 7(2):132-133
DOI
:10.4103/2229-5178.178093
PMID
:27057503
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1,094
185
1
Juvenile capillary hemangioma
Smeeta Gajendra, Rashmi Ranjan Das, Manas Kumar Sahoo
March-April 2016, 7(2):125-126
DOI
:10.4103/2229-5178.178079
PMID
:27057499
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1,062
197
1
CASES FROM ACKERMAN ACADEMY
A firm plaque on the cheek
Kara Melissa T Torres, Dirk M Elston, Dennis C Polley, Frank Ferritto
March-April 2016, 7(2):121-123
DOI
:10.4103/2229-5178.178101
PMID
:27057497
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1,060
170
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LETTERS TO THE EDITOR
Phakomatosis cesioflammea with bilateral frontal atrophy
Abhijeet Kumar Jha, Rajesh Sinha, Smita Prasad, Deepak Kumar
March-April 2016, 7(2):128-130
DOI
:10.4103/2229-5178.178077
PMID
:27057501
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974
141
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Multiple erythematous nodules in a 30-year-old woman
Shikha Gupta, Paschal D’souza, Tapan K Dhali
March-April 2016, 7(2):134-134
DOI
:10.4103/2229-5178.178095
PMID
:27057504
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781
140
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Authors reply: Multiple erythematous nodule in a 30-year-old woman
Martha Elena García-Meléndez, Kristian Eichelmann-Herrera, Osvaldo Tomás Vázquez-Martínez, Jorge Ocampo-Candiani
March-April 2016, 7(2):135-136
DOI
:10.4103/2229-5178.178092
PMID
:27057505
[FULL TEXT]
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525
45
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