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  Citation statistics : Table of Contents
   2015| July-August  | Volume 6 | Issue 4  
    Online since July 8, 2015

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Perforating granuloma annulare in a young male following application of the tattoo
Neha Kawatra Madan, Archana George Vallonthaiel, Sudheer Arava, Md Firdaus Ali, Mankul Goyal, Manoj Kumar Singh
July-August 2015, 6(4):296-298
DOI:10.4103/2229-5178.160286  PMID:26225344
  4 1,387 241
A tufted angioma
Aeerabolli Prasuna, Potharaju Narasimha Rao
July-August 2015, 6(4):266-268
DOI:10.4103/2229-5178.160259  PMID:26225332
Tufted angioma (TA) is a rare, benign, cutaneous angiomatous proliferation. It is more common in children, usually presenting as red-purple painful plaques on the trunk. We describe here a TA observed at nine months of age, appearing initially over the retroauricular area, gradually extending to involve skin of neck and trunk by two years of age. This case of a large TA (7 × 12 cm) in an Indian male child is reported here due to its rare presentation.
  3 2,452 289
Assessment of clinical diagnostic accuracy compared with pathological diagnosis of basal cell carcinoma
Ebrahimzadeh-Ardakani Mohammad, Moghimi Mansour, Kafaie Parichehr, Dehghani Farideh, Rashidi Amirhossein, Shojaoddiny-Ardekani Ahmad
July-August 2015, 6(4):258-262
DOI:10.4103/2229-5178.160257  PMID:26225330
Background: Basal cell carcinoma (BCC) is the most common type of skin cancer, afflicting light skin more than dark skin people. This malignancy metastasizes rarely and has unique histological properties. Aims and Objectives: We focused on the accuracy of clinical diagnoses of BCC by specialists. Materials and Methods: Patients' information for 4-year period between 2007 and 2011 was extracted from files at a Pathology Department. The results were analyzed using the Chi-square method and SPSS software. Results: From 367 referred cases dermatologists diagnosed 41% as direct BCC cases, 43.4% through excluding other skin diseases, 4% incorrectly and 1.11% unidentified. For other specialists (including plastic surgeons, ophthalmologists, general surgeons, and general practitioners) these were respectively 47.8%, 22.4%, 6.3% and 23.5%. Dermatologists had diagnosed 107 cases of all skin diseases as BCC through clinical examination of which 78.5% were correctly and 21.5% incorrectly diagnosed. The same parameters for all other specialists were respectively 77.36% and 22.64%. Diagnostic sensitivity, positive reportability, clinical conjecture indicator (CCI) and clinical diagnostic indicator were respectively 84.4%, 78.5%, 121.5% and 75.6%; whereas for other specialists these indicators were 70 among cases diagnosed by dermatologists as BCC, where pathological results showed other causes. The most common diagnosis by pathologists and other specialists was reported as squamous cell carcinoma (SCC). Among cases not diagnosed by dermatologists as BCC, where pathological results indicated BCC, the most common clinical diagnosis was malignant melanoma by dermatologists and SCC by other specialists. Conclusion: Dermatologists diagnosed BCC with higher sensitivity and positive reportability; also, CCIs and clinical diagnostic correctness was higher among dermatologists. The necessity for consulting with dermatologists and referring all skin diseases samplings to pathologist is thus clearly visible.
  3 1,292 293
Hair dye dermatitis and p-phenylenediamine contact sensitivity: A preliminary report
Mrinal Gupta, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan
July-August 2015, 6(4):241-246
DOI:10.4103/2229-5178.160253  PMID:26225326
Background: The contact allergic reactions from p-phenylenediamine (PPD) in hair dyes vary from mild contact dermatitis to severe life- threatening events (angioedema, bronchospasm, asthma, renal impairment). Objectives: To study the clinical patterns and PPD contact sensitivity in patients with hair-dye dermatitis. Materials and Methods: Eighty (M: F 47:33) consecutive patients aged between 18 and 74 years suspected to have contact allergy from hair dye were studied by patch testing with Indian Standard Series including p-phenylenediamine (PPD, 1.0% pet). Results: 54 Fifty-four (M: F 21:33) patients showed positive patch tests from PPD. Eight of these patients also showed positive patch test reaction from fragrance mix, thiuram mix, paraben mix, or colophony. Fifty-seven (71%) patients affected were aged older than 40 years. The duration of dermatitis varied from < 1 month to > 1 year with exacerbation following hair coloring. Forty-nine patients had dermatitis of scalp and/or scalp margins and 23 patients had face and neck dermatitis. Periorbital dermatitis, chronic actinic dermatitis, and erythema multiforme-like lesions were seen in 4, 2, and 1 patients, respectively. Conclusions: Hair dyes and PPD constitute a significant cause of contact dermatitis. There is an urgent need for creating consumer awareness regarding hair-dyes contact sensitivity and the significance of performing sensitivity testing prior to actual use.
  3 4,111 552
Correlation of serum antithyroid microsomal antibody and autologous serum skin test in patients with chronic idiopathic urticaria
Snehal Balvant Lunge, Milind Borkar, Sushil Pande
July-August 2015, 6(4):248-252
DOI:10.4103/2229-5178.160255  PMID:26225328
Background: About 25-45% of patients of chronic urticaria (CU) have been stated to have histamine releasing autoantibodies in their blood. The term autoimmune urticaria is increasingly being accepted for this subgroup of patients. Review of the literature suggests high autologous serum skin test (ASST) positivity and presence of antithyroid microsomal antibodies in patients with autoimmune urticaria. Aims: To study prevalence of ASST positivity and antithyroid microsomal antibodies in chronic "idiopathic" urticaria and to study the correlation between the two parameters. Methods: All patients of chronic idiopathic urticaria satisfying inclusion/exclusion criteria were enrolled in the study after written informed consent. Patients of CU secondary to infections and infestations, physical urticaria including dermatographism, mastocytosis, urticarial vasculitis and those on treatment with immunosuppressive drugs for urticaria were excluded from the study. In all of these patients, complete blood count; ASST, serum T3/T4/thyroid stimulating hormone levels, antithyroid microsomal antibody (AMA) levels were done. Statistical analysis was done by Chi-square test, Fisher exact test and Kappa statistics. Results: Study included 24 males and 26 females with mean age of 39.54 years. Majority of patients belonged to 20-40 years of age. Females showed more ASST positivity. A total of 12 out of 50 (24%) patients showed positive ASST. A total of four out of 12 (33.33%) had positive ASST and raised AMA levels. Conclusion: Only 25% of patients of chronic idiopathic urticaria had positive ASST. ASST and AMA levels were positively correlated in our study. Further studies are required to authenticate this association.
  2 1,504 351
Idiopathic eruptive macular pigmentation in a Chinese child
Zha Wei-Feng, Xu Ai-E, Chen Jun-Fan
July-August 2015, 6(4):274-276
DOI:10.4103/2229-5178.160266  PMID:26225334
We present a case of a healthy 8-year-old boy who presented with disseminated asymptomatic brown macules on the face, neck, trunk, and proximal extremities for 3 months. Dermatologic examination revealed multiple, smooth, nonscaly, brown macules involving the face, neck, trunk, and proximal limbs. The Darier's sign was negative. Histopathologic study showed normal epidermis and basal membrane, and increasingly scattered melanophages in the papillary dermis. The final diagnosis was idiopathic eruptive macular pigmentation.
  1 1,218 199
Intravascular papillary endothelial hyperplasia: An unusual histopathological entity
Qury S Mahapatra, Kavita Sahai, Ajay Malik, NS Mani
July-August 2015, 6(4):277-279
DOI:10.4103/2229-5178.160269  PMID:26225335
Intravascular papillary endothelial hyperplasia (Masson's tumor) is a benign lesion of the skin and subcutaneous tissue consisting of a reactive proliferation of endothelial cells with papillary formations related to a thrombus. It poses a diagnostic challenge as the clinical signs and symptoms are nonspecific and may mimic a soft tissue sarcoma. The diagnosis is based on histopathology. Here we report two cases of Masson's hemangioma occurring on the upper lip and on the left hand.
  1 2,195 273
Two cases of lymphangioma circumscriptum successfully treated with pulsed dye laser and cryotherapy
Ayse Serap Karadag, Emin Ozlu, Seyma Özkanlı, Tugba Kevser Uzuncakmak, Necmettin Akdeniz
July-August 2015, 6(4):291-293
DOI:10.4103/2229-5178.160283  PMID:26225341
  1 1,640 226
Expression of p16 in psoriasis and chronic spongiotic dermatitis
Viktoryia Kazlouskaya, Elina Shustef, Elen Blochin
July-August 2015, 6(4):300-301
DOI:10.4103/2229-5178.160289  PMID:26225346
  1 935 187
Serum levels of hypersensitive-C-reactive protein in moderate and severe acne
MR Namazi, AR Parhizkar, F Jowkar
July-August 2015, 6(4):253-257
DOI:10.4103/2229-5178.160256  PMID:26225329
Background: Elevation of C-reactive protein (CRP) has been reported to occur in psoriasis, urticaria, acne, rosacea and many other dermatological and nondermatological conditions. Chronic systemic inflammation has been implicated in the development of neuropsychiatric/degenerative disorders, atherosclerosis, coronary artery disease, diabetes mellitus and even carcinogenesis. The present study is designed to determine whether the level of inflammation created by acne vulgaris could be high enough to raise the serum levels of high-sensitive CRP. Materials and Methods: Forty-two patients with moderate and severe acne vulgaris were enrolled, along with 44 age and sex matched healthy blood donors as controls. Hypersensitive-CRP (Hs-CRP) was measured in both groups. Results: Hypersensitive-C-reactive protein levels in the case group varied between 0 and 28.1 μg/ml with an average of 2.24 ± 4.87 μg/ml (mean ± standard deviation) and a median of 0.6 μg/ml (interquartile range [IQR] =0.3, 1.4 μg/ml). Hs-CRP levels of the control group varied between 0 and 14 μg/ml with an average of 3.12 ± 3.67 μg/ml and a median of 1.5 μg/ml (IQR = 0.55, 5.0 μg/ml). No significant difference of Hs-CRP level between the two groups was seen (t = -0.961, 95% confidence interval: Lower = -2.6942, upper = 0.9377; P = 0.339). Additionally, no significant difference in the level of Hs-CRP was noted between the moderate and severe acne groups (95% confidence interval: Lower = -5.2495, upper = 1.6711; P = 0.165). Conclusion: Acne vulgaris, even in its severe grades (excluding acne fulminans and acne conglobata), does not induce significant inflammation at the systemic level.
  1 2,584 439
An atypical presentation of antiphospholipid antibody syndrome
Deepti D'Souza, Sukumar Dandakeri, M Ramesh Bhat, MK Srinath
July-August 2015, 6(4):263-265
DOI:10.4103/2229-5178.160258  PMID:26225331
Cutaneous manifestations in antiphospholipid antibody syndrome (APS) though common, are extremely diverse and it is important to know which dermatological finding should prompt consideration of antiphospholipid syndrome. The cutaneous manifestations of APS vary from livedo reticularis to cutaneous necrosis, and systemic involvement is invariably an accomplice in APS. Cutaneous ulcers with sharp margins can be seen in APS and they are usually seen on the legs. This case had an atypical presentation, as the initial presentation was painful necrotic ulcers over the legs, which resembled pyoderma gangrenosum and she had no systemic manifestations. There was no history of any arterial or venous thrombosis or any abortions. Antiphospholipid syndrome can be tricky to diagnose when cutaneous lesions are atypical. Nonetheless, it is very important to pin down this syndrome early due to its systemic complications.
  - 1,656 146
Merkel cell carcinoma of the abdominal wall
Vandana L Gaopande, Avinash R Joshi, Siddhi G.S. Khandeparkar, Sanjay D Deshmukh
July-August 2015, 6(4):269-273
DOI:10.4103/2229-5178.160262  PMID:26225333
Merkel cell carcinoma also known as neuroendocrine carcinoma of the skin is a very rare skin tumor. It commonly presents in the old age and the common sites are head, neck and extremities. The diagnosis requires histopathological examination with immunohistochemical correlation. We report a case of Merkel cell carcinoma stage IIIB with bilateral inguinal lymphadenopathy that on FNAB showed metastatic deposits of the tumor.
  - 1,157 193
Clinical course of disseminated Kaposi sarcoma in a HIV and hepatitis B co-infected heterosexual male
Manoj Kumar Agarwala, Renu George, Thambu David Sudarsanam, Raju Titus Chacko, Meera Thomas, Sheila Nair
July-August 2015, 6(4):280-283
DOI:10.4103/2229-5178.160271  PMID:26225336
AIDS associated Kaposi sarcoma (AIDS-KS) was first reported from India in 1993. Since then only 16 cases have been reported. Three of them had proven Human Herpesvirus 8 (HHV-8) infection. We report a case of disseminated KS in a heterosexual male from India with HIV, hepatitis B and HHV-8 infection. He was given six cycles of chemotherapy with liposomal doxorubicin over three months to which he showed a good response. The case highlights the clinical course and management of a HHV-8 positive disseminated KS in a patient co-infected with Hepatitis B and HIV.
  - 1,660 242
A solitary auricular polyp
Michael J McFall, John R Griffin, Dirk M Elston
July-August 2015, 6(4):284-285
DOI:10.4103/2229-5178.160276  PMID:26225337
  - 697 139
Dermpath Quiz
Najiyah Kazi, Erick Jacobson, Dirk Elston
July-August 2015, 6(4):286-287
DOI:10.4103/2229-5178.160277  PMID:26225338
  - 817 468
Treatment options of lymphangioma circumscriptum
Neerja Puri
July-August 2015, 6(4):293-294
  - 2,900 306
Hair dye dermatitis and para-phenylenediamine contact sensitivity
UK Sudhir Nayak
July-August 2015, 6(4):246-247
  - 2,026 261
Why do nails grow vertically?
Chander Grover
July-August 2015, 6(4):289-291
  - 988 198
Could cryosurgery be an alternative treatment for basal cell carcinoma of the vulva?: Erratum

July-August 2015, 6(4):314-314
DOI:10.4103/2229-5178.160308  PMID:26225353
  - 558 127
An interesting observation of polymorphous light eruption occurring on hypopigmented scars
Pradeep Balasubramanian, Soumya Jagadeesan, Lalitha Sekar, Jacob Thomas
July-August 2015, 6(4):294-296
DOI:10.4103/2229-5178.160285  PMID:26225343
  - 2,191 194
A rare areolar growth developing late in pregnancy
Shikha Seth, Pinki Pandey, Rajani Rawat, Soniya Vishwakarma
July-August 2015, 6(4):298-300
DOI:10.4103/2229-5178.160287  PMID:26225345
  - 3,061 166
Vertically growing nail - A rare entity
Prachi Barad, Joycelin Fernandes, Rakhi Ghodge, Pankaj Shukla
July-August 2015, 6(4):288-289
DOI:10.4103/2229-5178.160279  PMID:26225339
  - 2,055 189
SkIndia Quiz 19: Soft tumors in segmental fashion
Mahendra M Kura, Sumit Parsewar
July-August 2015, 6(4):302-303
DOI:10.4103/2229-5178.156541  PMID:26225347
  - 1,753 225
Eccrine poroma
Vaishali Wankhade, Rajesh Singh, Venus Sadhwani, Purnima Kodate
July-August 2015, 6(4):304-305
DOI:10.4103/2229-5178.160296  PMID:26225348
  - 1,709 246
Porokeratotic eccrine ostial and dermal duct nevus: Case report of a rare entity
Krina B Patel
July-August 2015, 6(4):306-307
DOI:10.4103/2229-5178.160299  PMID:26225349
  - 696 172
Osler's sign revisited
Annapurna Kumar, Kaliaperumal Karthikeyan, Malhar T Vyas
July-August 2015, 6(4):308-309
DOI:10.4103/2229-5178.160302  PMID:26225350
  - 1,984 215
Plica neuropathica
Lalit Kumar Gupta, Manisha Balai, Ashok Kumar Khare, Asit Mittal
July-August 2015, 6(4):310-311
DOI:10.4103/2229-5178.160304  PMID:26225351
  - 1,723 186
Neonatal umbilical myiasis
Arvind Kumar Singh, Shankha Subhra Nag, Piyali Mitra, Atanu Roy
July-August 2015, 6(4):312-313
DOI:10.4103/2229-5178.160306  PMID:26225352
  - 1,259 191
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