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  Citation statistics : Table of Contents
   2015| November-December  | Volume 6 | Issue 6  
    Online since November 17, 2015

 
 
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ORIGINAL ARTICLES
Diagnostic value of Tzanck smear in various erosive, vesicular, and bullous skin lesions
Atiya Yaeen, Qazi Masood Ahmad, Anjum Farhana, Parveen Shah, Iffat Hassan
November-December 2015, 6(6):381-386
DOI:10.4103/2229-5178.169729  PMID:26751561
Background: Cutaneous cytology has long been shown to be useful in the diagnosis of several erosive, vesicular, and bullous skin lesions. The Tzanck smear although an old tool, still remains a simple, rapid, easily applied, and inexpensive test for these skin lesions. Aims and Objectives: The aim of this study was to evaluate the diagnostic value of Tzanck smear by determining its sensitivity and specificity in various erosive, vesicular, and bullous skin lesions. Materials and Methods: One hundred and forty-two patients with erosive, vesicular, and/or bullous skin lesions were included in the study. Four groups of disorders were identified: infections, immunologic disorders, genodermatosis, and spongiotic dermatitis. All the study cases were evaluated by Tzanck smear. Definitive diagnosis was established by standard diagnostic techniques (including when appropriate, viral serology, bacterial culture, histopathology, direct immunoflourescence). Results: The sensitivity and specificity of cytologic findings was respectively 86.36% and 91.30% for viral infections; for bacterial infections, it was 85.7% and 66.6%. The sensitivity and specificity of Tzanck smear was respectively 85.0% and 83.33% for pemphigus; for bullous pemhigoid it was 11.11% and 100.0%. Tzanck smear sensitivity in genodermatoses was 100%. The sensitivity and specificity of the test in spongiotic dermatitis could not be calculated due to an insufficient number of patients. Conclusion: The Tzanck smear is a quick and reliable tool for the evaluation of various erosive and vesiculobullous skin lesions.
  4 10,840 1,153
CASE REPORTS
Kaposi's varicelliform eruption: A case series
Bruno Ferrari, Vanina Taliercio, Paula Luna, María Eugenia Abad, Margarita Larralde
November-December 2015, 6(6):399-402
DOI:10.4103/2229-5178.169714  PMID:26753139
Kaposi's varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. It concomitantly occurs with pre-existing skin conditions, mostly atopic dermatitis, so it is predominately found in children. We present a case series that includes four adults, familial cases, and previously healthy patients. We also highlight clinical features, associations and therapeutic options.
  3 3,604 391
Gianotti-Crosti Syndrome following immunization in an 18 months old child
Thirunavukkarasu Arun Babu, Avinash Arivazhahan
November-December 2015, 6(6):413-415
DOI:10.4103/2229-5178.169713  PMID:26751677
Gianotti-Crosti syndrome (GCS) is an uncommon dermatological condition characterized by distinct, self-limiting, symmetrical, erythematous, papulovesicular eruptions distributed mainly on the extremities, buttocks and face in young children. Although GCS is commonly attributed to viral infections, vaccinations too can rarely precipitate this condition. We report a rare case of GCS following diptheria, pertussis, and tetanus (DPT) and oral polio immunisation in an 18-month-old child along with a review of similar vaccine-induced GCS cases reported in the literature.
  3 3,620 272
CASES FROM ACKERMAN ACADEMY
Multiple nodules on the sole of the foot
Alyssa J Miceli, Jacqueline M Junkins-Hopkins, Dennis C Polley, Dirk M Elston
November-December 2015, 6(6):422-424
DOI:10.4103/2229-5178.169720  PMID:26753144
Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations.
  3 1,528 241
CASE REPORTS
Naegeli-Franceschetti-Jadassohn syndrome: A rare case
Bela J Shah, Ashish K Jagati, Neha P Gupta, Suyog S Dhamale
November-December 2015, 6(6):403-406
DOI:10.4103/2229-5178.169712  PMID:26753140
Naegeli-Franceschetti-Jadassohn Syndrome (NFJS) is a rare, autosomal dominant inherited form of ectodermal dysplasia, caused by mutation in the KRT14 gene. We report here a case of NFJS in a 27-year-old male who presented with reticulate hyperpigmentation over skin, dental changes, absence of dermatoglyphics, hypohidrosis, and hair changes.
  2 4,106 378
LETTER TO THE EDITOR
Porokeratosis and malignant melanoma: A causal or incidental association?
Leonor Neto Lopes, Ana Isabel Gouveia, Luís Soares-Almeida, Manuel Sacramento-Marques, Paulo Filipe
November-December 2015, 6(6):451-452
DOI:10.4103/2229-5178.169736  PMID:26753152
  2 919 159
ORIGINAL ARTICLES
Clinical study of cutaneous leishmaniasis in the Kashmir Valley
Gh Mohiuddin Wani, Sheikh Manzoor Ahmad, Bilques Khursheed
November-December 2015, 6(6):387-392
DOI:10.4103/2229-5178.169732  PMID:26753136
Background: Cutaneous leishmaniasis (CL) is an infectious disease of tropical and semitropical areas of the world. The cold and harsh winter conditions of the Kashmir Valley do not favor the survival and growth of the Leishmania parasite or its vector, the sand fly, and the disease was until now practically unheard of in the Kashmir Valley. Aims: There has been a recent rise in the number of cases of CL in the Kashmir Valley. Against this background, the present study was taken up to describe the epidemiology, clinical features, and management outcomes of CL in the Kashmir Valley, where it represents a new phenomenon. Materials and Methods: Patients with direct smear-confirmed CL were evaluated. For each patient, we noted age, gender, geographical origin, stays in endemic areas, clinical aspects, number, site and size of lesions, treatment, and outcome. All the infected patients were treated with sodium stibogluconate. The dose, route of administration, adverse effects, and the clinical response in each patient was noted down. Results: Eighteen patients, 11 males (61.12%) and 7 females (38.88%) were studied. The age of the patients ranged from 3 to 60 years (mean age 29.8). The majority of our patients (16, 88.9%) belonged to two hilly areas, Uri and Karnah. Duration of the disease ranged from a minimum of 1 month to a maximum of 18 months (mean duration 4.6 months). Lesions in most of our patients (16, 88.9%) were located on the face including the lip and nose. The size of lesions varied from 4 to about 50 mm (average 2-3 cm). Most of our patients (13, 73.3%) had only a single lesion and a few (5, 26.7%) had two or three lesions. The clinical type of lesion in most of our patients (16, 88.9%) was noduloulcerative, only two (11.1%) had nodular (nonulcerative) lesions. Sixteen patients; all with facial lesions were treated with intravenous sodium stibogluconate. A complete response was seen in 14 (87%), without any major adverse effect. Two adult patients with extrafacial lesions were treated with four doses of weekly intralesional injections of sodium stibogluconate. A complete response was seen in both, without any major adverse effect. Conclusion: The emergence of CL in this nonendemic area is of great epidemiological importance. Because no parasite isolation and characterization was carried out, further epidemiological studies and taxonomic differentiation of the species are required.
  2 2,042 284
CASE REPORTS
Conidiobolomycosis: A case report of rare fungal infection from the eastern India
Somashree Dutta, Somenath Sarkar, Uttam Linka, Sujata Dora
November-December 2015, 6(6):393-395
DOI:10.4103/2229-5178.169715  PMID:26753137
Conidiobolomycosis is a rare chronic subcutaneous mycosis of nose and paranasal sinuse predominately affects the middle age men in tropical countries. It is caused by a saprophytic fungus "Conodiobolus coronatus", which can survives in soils and dried vegetables for long period of time. C. coronatus belongs to the class Zygomycetes, order Entomophthorales. It is a fungus composed of thick- walled, short hyphae that grows at temperatures of 30 to 37 degrees C. Here we report a case of conidiobolomycosis in a 55- year- old farmer presented with a subcutaneous swelling over the left side of nose extending to left cheek.
  1 2,206 282
Carcinoma erysipeloides as a presenting feature of breast carcinoma: A case report and brief review of literature
Ali Al Ameer, Maryam Imran, Feroze Kaliyadan, Rajan Chopra
November-December 2015, 6(6):396-398
DOI:10.4103/2229-5178.169724  PMID:26753138
Carcinoma erysipeloides (CE) is an uncommon but distinctive form of cutaneous metastasis that usually manifests clinically as a fixed erythematous patch or plaque resembling cellulitis or erysipelas. The inflamed area may show a distinct raised edge at the periphery and also edema secondary to lymphatic obstruction. Histologically, dense carcinoma cells in the dermal vascular channels and dense perivascular lymphocytic infiltrate may be seen. CE may rarely be the first sign of “silent” tumor of breast. We report a case of a 52-year-old married lady who presented with a three months history of pruritic erythematous patches over the left side of the breast that was resistant to all topical treatments and was diagnosed as erysipeloid breast carcinoma.
  1 2,644 301
Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide
Radhakrishnan Subramaniyan, Rajagopal Ramachandran, Gnanasekaran Rajangam, Navya Donaparthi
November-December 2015, 6(6):407-409
DOI:10.4103/2229-5178.169743  PMID:26753141
Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide.
  1 1,360 237
Subcutaneous entomophthoromycoses
Tadepalli Karuna, Dinesh P Asati, Debasis Biswas, Shashank Purwar
November-December 2015, 6(6):410-412
DOI:10.4103/2229-5178.169730  PMID:26753142
Subcutaneous entomophthoromycoses is a zygomycosis caused by Basidiobolus ranarum that is endemic in southern India. We report the case of a 63-year-old male from central India who presented with a nontender subcutaneous hyperpigmented plaque on his leg with mild discharge that yielded Basidiobolus ranarum.
  1 1,648 216
LETTERS TO THE EDITOR
Rituximab therapy in a case of pemphigus vulgaris triggering herpes simplex infection at varied sites
Kiran K Chotaliya, Richa Gupta, Yogesh S Marfatia
November-December 2015, 6(6):444-446
DOI:10.4103/2229-5178.169722  PMID:26753151
  1 1,506 251
MUSINGS, OPINIONS, TIPS AND EXPERIENCES
Global leprosy program: Does it need uniform-multi-drug therapy now?
P Narasimha Rao, Sunil Dogra, Sujai Suneetha
November-December 2015, 6(6):425-427
DOI:10.4103/2229-5178.169735  PMID:26753145
  1 2,510 382
THROUGH THE LENS
Extensive terra firma forme dermatosis [TFFD]: A rare presentation
Komal Panchal, Neha Bhalla, Pranjal Salunke, Hemangi Jerajani
November-December 2015, 6(6):458-459
DOI:10.4103/2229-5178.169742  PMID:26752293
  1 2,714 207
Acrokeratoelastoidosis
Kinjal D Rambhia, Uday S Khopkar
November-December 2015, 6(6):460-461
DOI:10.4103/2229-5178.169718  PMID:26753156
  1 2,445 261
CASES FROM ACKERMAN ACADEMY
Dermatopathology quiz: Cerebriform papules of the scrotum
Cassondra Andreychik, Leonard J Bernstein, Dirk Elston
November-December 2015, 6(6):416-418
DOI:10.4103/2229-5178.169719  PMID:26751781
  - 3,603 199
Asymptomatic erythematous plaque
Olga V Udovenko, John R Griffin, Dirk M Elston
November-December 2015, 6(6):419-421
DOI:10.4103/2229-5178.169721  PMID:26753143
  - 2,632 182
COMMENTARY
Porokeratosis and malignancy: Incidental or causal association?
Najeeba Riyaz
November-December 2015, 6(6):452-453
PMID:26753153
  - 764 146
Granuloma faciale: A master masquerader?
Najeeba Riyaz
November-December 2015, 6(6):450-451
PMID:26752188
  - 713 155
DRUG PROFILE
Aspirin in dermatology: Revisited
Aditya Kumar Bubna
November-December 2015, 6(6):428-435
DOI:10.4103/2229-5178.169731  PMID:26753146
Aspirin has been one of the oldest drugs in the field of medicine, with a wide range of applications. In dermatology, aspirin has shown benefit in a variety of disorders. Recently, reduction of melanoma risk with aspirin has been demonstrated. Although an analgesic to begin with, aspirin has come a long way; after cardiology, it is now found to be useful even in dermatology.
  - 3,933 508
EDITORIAL
Bidding adieu
Shyam Verma
November-December 2015, 6(6):379-380
DOI:10.4103/2229-5178.169734  PMID:26753135
  - 1,870 230
LETTERS TO THE EDITOR
Aneurysmal benign fibrous histiocytoma presenting as a giant acrochordon on thigh
Anupam Das, Anirban Das, Debabrata Bandyopadhyay, Vivek Mishra, Abanti Saha
November-December 2015, 6(6):436-438
DOI:10.4103/2229-5178.169740  PMID:26753147
  - 1,329 202
Hutchinson-Gilford progeria syndrome
Amar Singh Bhukya, Bellum Siva Nagi Reddy
November-December 2015, 6(6):438-440
DOI:10.4103/2229-5178.169733  PMID:26753148
  - 1,483 254
Necrotizing fasciitis associated with systemic lupus erythematosus in a child
Sahana M Srinivas, Alkarani T Patil, Gowri Shankar, Keshavmurthy M Lakshmikantha, Munirathnam Govindraj
November-December 2015, 6(6):441-442
DOI:10.4103/2229-5178.169737  PMID:26753149
  - 874 174
A postoperative case of carcinoma erysipeloides arising from ductal carcinoma of the breast
Shankar Sathish, Talari Srinivas Rajashekar, Bittanakurike Narasappa Raghavendra, Gurumurthy Rajesh
November-December 2015, 6(6):443-444
DOI:10.4103/2229-5178.169710  PMID:26753150
  - 999 151
Acute generalized exanthematous pustulosis due to meropenem: An unusual side effect of a commonly used drug
Loknath Ghoshal, Saumen Nandi, Aritra Sarkar, Sudip Das
November-December 2015, 6(6):446-448
DOI:10.4103/2229-5178.169711  PMID:26751943
  - 773 187
Granuloma faciale
Deepti Kataria, Swagata Tambe, Chitra S Nayak
November-December 2015, 6(6):448-449
DOI:10.4103/2229-5178.169741  PMID:26752060
  - 2,094 201
SKINDIA QUIZ
SkIndia Quiz 21: Recurrent papulonodular lesions on elbows, fingers and lower leg
Anupam Das, Indrani Das, Anupama Ghosh, Piyush Kumar, Nilay K Das, Ramesh C Gharami
November-December 2015, 6(6):454-455
DOI:10.4103/2229-5178.164579  PMID:26753154
  - 2,081 194
THROUGH THE LENS
Linear rays of depigmentation along lymphatics after intralesional corticosteroid therapy
Kameshwar Prasad, Bhushan Madke, Sumit Kar, Amit K Sinha, Nidhi Yadav
November-December 2015, 6(6):456-457
DOI:10.4103/2229-5178.169728  PMID:26753155
  - 1,173 150
Acute and dramatic saxophone penis
Carlota Gutiérrez García-Rodrigo, Lidia Maroñas-Jimenéz, Diana Menis, Hugo Larráin, Lara Angulo Martínez
November-December 2015, 6(6):462-463
DOI:10.4103/2229-5178.169726  PMID:26752411
We present a case of intense genital swelling because of a hereditary angioedema. This rare disease should be included in the differential diagnosis of acute and asymptomatic genital edema, because it may prevent future potentially life-threatening episodes of visceral angioedema.
  - 1,049 117
Urticaria pigmentosa
Resham J Vasani, Sudhir V Medhekar
November-December 2015, 6(6):464-465
DOI:10.4103/2229-5178.169727  PMID:26752589
  - 1,210 262
Scrotal calcinosis
Sweta Rambhia, Bhanu Prakash
November-December 2015, 6(6):466-466
DOI:10.4103/2229-5178.169725  PMID:26753157
  - 3,291 201
A seemingly insignificant lesion
Anahita Sadeghi, Mohammad Biglari
November-December 2015, 6(6):467-468
DOI:10.4103/2229-5178.169723  PMID:26753158
  - 1,837 180
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