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  Indian J Med Microbiol
 

Figure 3: (a) A tumor composed of sheets of large, round to polygonal cells with ill-defined cytoplasmic borders (H and E, × 10); (b and c) the tumor cells have abundant granular eosinophilic cytoplasm, round to oval centrally or eccentrically located nuclei with occasional small nucleoli. Eosinophilic ovoid bodies are surrounded by a clear halo (arrow and circle) (H and E, ×40). On immunohistochemistry, (d) the tumor cells show strong cytoplasmic positivity for the S-100 protein (H and E, ×40); (e) the tumor cells show positivity for vimentin (H and E, ×40); (f) the tumor cells are negative for CD68 (H and E, ×40)

Figure 3: (a) A tumor composed of sheets of large, round to polygonal cells with ill-defined cytoplasmic borders (H and E, × 10); (b and c) the tumor cells have abundant granular eosinophilic cytoplasm, round to oval centrally or eccentrically located nuclei with occasional small nucleoli. Eosinophilic ovoid bodies are surrounded by a clear halo (arrow and circle) (H and E, ×40). On immunohistochemistry, (d) the tumor cells show strong cytoplasmic positivity for the S-100 protein (H and E, ×40); (e) the tumor cells show positivity for vimentin (H and E, ×40); (f) the tumor cells are negative for CD68 (H and E, ×40)