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  Indian J Med Microbiol
 

Figure 10: Confocal microscope images of melasma showing epidermal pigmentation: (a) Melasma on the cheek. L is for lesional skin and N is for normal perilesional skin. (b) Confocal images depict cobblestoning and loss of dermal papillary rings at the basal layer of the melasma lesion (L) compared to perlesional normal skin (N). Scale bar: 50 um. (c) Histopathology from same lesion showing greater epidermal hyperpigmentation and flattened rete ridges in lesion compared to perilesional normal skin Fontana-Masson staining, horizontal line indicates where reflectance confocal microscopy image is taken from (source acknowledged: Kang HY, Bahadoran P, Ortonne JP. Reflectance confocal microscopy for pigmentary disorders. Exp Dermatol 2010;19:233-9)

Figure 10: Confocal microscope images of melasma showing epidermal pigmentation: (a) Melasma on the cheek. L is for lesional skin and N is for normal perilesional skin. (b) Confocal images depict cobblestoning and loss of dermal papillary rings at the basal layer of the melasma lesion (L) compared to perlesional normal skin (N). Scale bar: 50 um. (c) Histopathology from same lesion showing greater epidermal hyperpigmentation and flattened rete ridges in lesion compared to perilesional normal skin Fontana-Masson staining, horizontal line indicates where reflectance confocal microscopy image is taken from (source acknowledged: Kang HY, Bahadoran P, Ortonne JP. Reflectance confocal microscopy for pigmentary disorders. Exp Dermatol 2010;19:233-9)