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  Indian J Med Microbiol
 

Figure 1: (a) The right leg and foot shows elephantiasis with the presence of multiple nodules in the foot. (b) The nests of hyperchromatic tumor cells are seen throughout the dermis. The epithelium shows hyperkeratosis and papillomatosis (hematoxylin and eosin stain ×100 magnification). (c) The tumor cells are epithelioid shaped, hyperchromatic nuclei with prominent macronucleoli (hematoxylin and eosin stain ×400 magnification). (d) Immunohistochemistry showing strong expression of HMB45 (immunohistochemistry: avidin–biotin method with DAB chromogen and hematoxylin counterstain, ×400 magnification)

Figure 1: (a) The right leg and foot shows elephantiasis with the presence of multiple nodules in the foot. (b) The nests of hyperchromatic tumor cells are seen throughout the dermis. The epithelium shows hyperkeratosis and papillomatosis (hematoxylin and eosin stain ×100 magnification). (c) The tumor cells are epithelioid shaped, hyperchromatic nuclei with prominent macronucleoli (hematoxylin and eosin stain ×400 magnification). (d) Immunohistochemistry showing strong expression of HMB45 (immunohistochemistry: avidin–biotin method with DAB chromogen and hematoxylin counterstain, ×400 magnification)