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  Indian J Med Microbiol
 

Figure 5: Upper panel: Langerhans cell histiocytosis. (a) Atypical histiocytes with grooved nuclei present in the dermis. Background shows many eosinophils (HE, ×200). The tumor cells diffusely express (b) CD1a (×100) and (c) S-100 (×100). Lower panel: Reticulohistiocytoma. (d) Presence of sheets of atypical histiocytes in the dermis (HE, ×100). (e) The tumor cells have abundant eosinophilic cytoplasm (HE, ×200). (f) Tumor cells show diffuse CD68 expression (×100)

Figure 5: Upper panel: Langerhans cell histiocytosis. (a) Atypical histiocytes with grooved nuclei present in the dermis. Background shows many eosinophils (HE, ×200). The tumor cells diffusely express (b) CD1a (×100) and (c) S-100 (×100). Lower panel: Reticulohistiocytoma. (d) Presence of sheets of atypical histiocytes in the dermis (HE, ×100). (e) The tumor cells have abundant eosinophilic cytoplasm (HE, ×200). (f) Tumor cells show diffuse CD68 expression (×100)