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  Indian J Med Microbiol
 

Figure 2: Pharmacokinetic profile of oral itraconazole in human skin 100 mg × 4 weeks and after stopping therapy. This reveals that the level of the drug varies with a higher level in the sebum rich areas of skin as compared to plasma but the levels in the skin are consistently higher than serum levels with a peak level at 21 days (Plasma levels μg/mL; skin levels μg/gm)

Figure 2: Pharmacokinetic profile of oral itraconazole in human skin 100 mg × 4 weeks and after stopping therapy. This reveals that the level of the drug varies with a higher level in the sebum rich areas of skin as compared to plasma but the levels in the skin are consistently higher than serum levels with a peak level at 21 days (Plasma levels <b>μ</b>g/mL; skin levels <b>μ</b>g/gm)