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  Indian J Med Microbiol
 

Figure 1: Cytokine flow chart (Diagram credit: Dr Sandeep Arora) SARS CoV2 virion in environment reaches the A. Alveolus where it enters the alveolar cell lining with the help of ACE2 receptor. B. Macrophages process and presenting the viral components to T and B cell C. T cell differentiation leads to activated T cells which induce D. Th1, Th2, and Th17 response E. Cytokines released promote an influx of inflammatory cells: neutrophils, monocytes, and macrophages F. Rapid cytokine release and further recruitment leads the cytokine storm. G. Macrophage also causes activation of B cells causes release of antibodies which help neutralize the virion * Release of ILs (6,12,23,17, TNF cause psoriasis flares. They can also be inhibited by monoclonal antibodies which are used to treat psoriasis. These monoclonal antibodies are marked at specific sites in the figure

Figure 1: Cytokine flow chart (Diagram credit: Dr Sandeep Arora) SARS CoV2 virion in environment reaches the A. Alveolus where it enters the alveolar cell lining with the help of ACE2 receptor. B. Macrophages process and presenting the viral components to T and B cell C. T cell differentiation leads to activated T cells which induce D. Th1, Th2, and Th17 response E. Cytokines released promote an influx of inflammatory cells: neutrophils, monocytes, and macrophages F. Rapid cytokine release and further recruitment leads the cytokine storm. G. Macrophage also causes activation of B cells causes release of antibodies which help neutralize the virion * Release of ILs (6,12,23,17, TNF cause psoriasis flares. They can also be inhibited by monoclonal antibodies which are used to treat psoriasis. These monoclonal antibodies are marked at specific sites in the figure